Evidence map›Paper›PMID 40417811›Full record

ArticleJournal of the American Heart Association2025

Differences in In-Hospital and Post-Discharge Ischemic Stroke Care According to Prestroke Functional Status.

Paul M Wechsler, Eva A Mistry, Heidi Sucharew, David J Robinson, Robert Stanton, Felipe de Los Rios La Rosa, Jason Mackey, Simona Ferioli, Stacie L Demel, Elisheva R Coleman and 9 more

Abstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Paul M WechslerUniversity of Cincinnati OH USA.ORCID 0000-0002-0314-1867
Eva A MistryUniversity of Cincinnati OH USA.ORCID 0000-0002-7426-3650
Heidi SucharewUniversity of Cincinnati OH USA.ORCID 0000-0002-3933-1574
David J RobinsonUniversity of Cincinnati OH USA.ORCID 0000-0003-3221-3599
Robert StantonUniversity of Cincinnati OH USA.ORCID 0000-0003-3804-5063
Felipe de Los Rios La RosaMiami Neuroscience Institute Baptist Health South Florida Miami FL USA.ORCID 0000-0003-4465-9280
Jason MackeyIndiana University Indianapolis IN USA.ORCID 0000-0002-6867-8630
Simona FerioliUniversity of Cincinnati OH USA.ORCID 0000-0001-6534-3029
Stacie L DemelUniversity of Cincinnati OH USA.ORCID 0000-0002-3000-8420
Elisheva R ColemanUniversity of Chicago IL USA.ORCID 0000-0002-7565-432X
Adam JasneYale University New Haven CT USA.ORCID 0000-0001-9092-3607
Sabreena SlavinUniversity of Kansas Kansas City KS USA.
Kyle B WalshUniversity of Cincinnati OH USA.ORCID 0000-0002-1178-6286
Michael StarSoroka Medical Center Beersheva Israel.
Mary HaverbuschUniversity of Cincinnati OH USA.ORCID 0000-0002-1017-1036
Kathleen AlwellUniversity of Cincinnati OH USA.ORCID 0000-0003-1620-4721
Daniel WooUniversity at Buffalo Buffalo NY USA.ORCID 0000-0002-2466-7155
Dawn O KleindorferUniversity of Michigan Ann Arbor MI USA.ORCID 0000-0003-1361-3693
Brett M KisselaUniversity of Cincinnati OH USA.ORCID 0000-0002-9773-4013

Funding

The Subdural Hematoma Outcomes in a Population (SD HOP) StudyK23NS121633 · NINDS · UNIVERSITY OF CINCINNATI · PI David Robinson · 2023 to 2026
$927k
NINDS NIH HHS K23 NS121633
6 · The paper itself

Abstract

backgroundLimited data exist regarding differences in ischemic stroke care across the care continuum between patients with and without prestroke disability. We investigated differences in in-hospital and postdischarge ischemic stroke cause evaluation and treatment between patients with and without prestroke disability using population-based data in the United States.

methodsWe ascertained all adult patients (≥18 years) hospitalized with acute ischemic stroke within the Greater Cincinnati/Northern Kentucky population between January 1, 2015, and December 31, 2015. We used univariate analyses and logistic regression to compare differences in acute ischemic stroke reperfusion therapies, stroke cause evaluation, prescription of secondary stroke prevention treatments, and rehabilitation between patients with prestroke disability (modified Rankin Scale score ≥2) and those without prestroke disability (modified Rankin Scale score 0-1).

resultsOf 2476 ischemic stroke patients, 1326 (53%) had prestroke disability. Prestroke disability was associated with lower odds of receiving thrombolysis (adjusted odds ratio [aOR], 0.43 [95% CI, 0.28-0.68],

conclusionFurther research into factors driving medical decision-making for patients with prestroke disability is needed to optimize the entire spectrum of ischemic stroke care for this population.

Indexed as

Functional StatusIschemic StrokePatient DischargeStroke RehabilitationAgedAged, 80 and overDisability EvaluationEndovascular ProceduresFemaleHumansKentuckyMaleMiddle AgedRetrospective StudiesSecondary PreventionThrombectomydisabilityischemic strokeprevention

Identifiers

PMID40417811
PMCPMC12229213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.