Evidence map›Paper›PMID 40417800›Full record

ArticleJournal of the American Heart Association2025

Climate Vulnerability and Cardiovascular-Kidney-Metabolic Disease in the United States.

Pedro Rafael Vieira de Oliveira Salerno, P Grace Tee Lewis, Zhuo Chen, Jean-Eudes Dazard, Sarju Ganatra, Eman Nayaz Ahmed, Khurram Nasir, Salil V Deo, Sanjay Rajagopalan, Sadeer Al-Kindi

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Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pedro Rafael Vieira de Oliveira SalernoDepartment of Medicine NYC Health+Hospitals/Elmhurst, Icahn School of Medicine at Mt. Sinai Queens NY USA.ORCID 0000-0002-5116-5062
P Grace Tee LewisEnvironmental Defense Fund Houston TX USA.ORCID 0000-0002-2345-1846
Zhuo ChenHarrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center Cleveland OH USA.ORCID 0000-0001-7781-2080
Jean-Eudes DazardHarrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center Cleveland OH USA.ORCID 0000-0003-4720-3684
Sarju GanatraDepartment of Medicine Lahey Clinic Burlington MA USA.ORCID 0000-0003-0296-6864
Eman Nayaz AhmedDepartment of Cardiology Houston Methodist Hospital Houston TX USA.
Khurram NasirDepartment of Cardiology Houston Methodist Hospital Houston TX USA.ORCID 0000-0001-5376-2269
Salil V DeoSurgical Services, Louis Stokes Cleveland Cleveland OH USA.ORCID 0000-0002-4729-1461
Sanjay RajagopalanHarrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center Cleveland OH USA.ORCID 0000-0001-6669-8163
Sadeer Al-KindiDepartment of Cardiology Houston Methodist Hospital Houston TX USA.ORCID 0000-0002-1122-7695

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is an incomplete understanding of the impact of climate change on cardiovascular-kidney-metabolic (CKM) syndrome. Although climate change affects all Americans, certain communities and individuals may suffer a disproportionate burden. Therefore, this study's objective was to explore the relationship between the Climate Vulnerability Index domains and the prevalence of CKM components in the United States.

methodsThis cross-sectional study obtained health outcomes from Centers for Disease Control and Prevention Population Level Analysis and Community Estimates (2021) and assessed the census tract-level prevalence of coronary heart disease, chronic kidney disease, obesity, diabetes, dyslipidemia, and hypertension. ANOVA was used to assess statistically significant differences in the means of CKM components between quartiles of each climate change domain. Linear regression models assessed the association between each domain and outcome, followed by models adjusted by baseline Climate Vulnerability Index components. Fully adjusted models included all 3 climate change domains and the baseline Climate Vulnerability Index components.

resultsData for 70 300 census tracts, covering 299.8 million individuals, were included. Statistically significant differences (

conclusionsThe Climate Vulnerability Index's climate change component was associated with the prevalence of CKM components (coronary heart disease, chronic kidney disease, obesity, diabetes, dyslipidemia, and hypertension). These findings suggest that populations with CKM may be associated with increased climate vulnerability, underscoring the need for a deeper understanding of climate change as a determinant of health.

Indexed as

Cardiovascular DiseasesClimate ChangeMetabolic SyndromeRenal Insufficiency, ChronicAgedCross-Sectional StudiesDyslipidemiasFemaleHumansHypertensionMaleMiddle AgedPrevalenceRisk AssessmentRisk FactorsUnited Statescardiovascular‐kidney‐metabolic syndromeclimate vulnerability indexsocial determinants of health

Identifiers

PMID40417800
PMCPMC12229176

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.