Evidence map›Paper›PMID 40417763›Full record

ArticleCurrent rheumatology reviews2026

Uncommon Presentation of Giant Tophaceous Gout in the Hand: A Case Report.

Hassan Zmerly, Ibrahim Akkawi, Damiano Alfio Ruinato, Manuela Moscato, Maurizio Draghetti, Francesco Pegreffi

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Article in Current rheumatology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hassan ZmerlyOrthopaedics and Traumatology Unit, Villa Erbosa Hospital, Bologna, Italy.ORCID 0000-0003-3353-1759
Ibrahim AkkawiOrthopaedics and Traumatology Unit, Villa Erbosa Hospital, Bologna, Italy.ORCID 0000-0003-3972-5968
Damiano Alfio RuinatoOrthopaedics and Traumatology Unit, Villa Erbosa Hospital, Bologna, Italy.
Manuela MoscatoOrthopaedics and Traumatology Unit, Villa Erbosa Hospital, Bologna, Italy.
Maurizio DraghettiOrthopaedics and Traumatology Unit, Villa Erbosa Hospital, Bologna, Italy.
Francesco PegreffiDepartment of Medicine and Surgery, School of Medicine and Surgery, Kore University, Enna, Italy.ORCID 0000-0002-6788-6040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTophaceous gout masses are characterized by the accumulation of monosodium urate crystals in peripheral joints and soft tissues. The most commonly involved areas are the metatarsophalangeal and knee joints. Finger/hand localization is uncommon. If not correctly treated, a finger tophaceous mass can grow and, in rare cases, reach an abnormally large size, termed "giant."

aimThe aim of our study is to present a rare case of a large tophaceous mass of the hand, localized in the fourth finger, and to highlight the role of surgical excision combined with a multidisciplinary team approach. CASE REPORT: We present a rare case of an 82-year-old woman affected by giant tophaceous gout in the left hand, localized to the extensor region of the proximal interphalangeal joint of the fourth finger. Clinical evaluation, MRI, and ultrasound imaging showed a 35 x 30 mm nodule in the soft tissue. The lesion was successfully treated by mass excision and debridement of the extensor tendon. Histopathologic examination confirmed the diagnosis of tophaceous gout. Post-operatively, a combination of medical and nutritional therapy was given. At a 3-year follow-up, the patient was free of symptoms with no evidence of disease in the fourth finger.

conclusionManagement of giant tophaceous gout in hand necessitates extensive mass excision combined with pharmacological therapy, dietary adjustments, and lifestyle modifications. Effective treatment of such cases requires a multidisciplinary team approach to address the complexity of the condition comprehensively.

Indexed as

Finger JointGoutHandAged, 80 and overFemaleHumansGoutinterphalangeal jointmulti disciplinary approach.nodule excisionpharmacological therapytophaceous mass

Identifiers

PMID40417763
PMCPMC13223452

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