Evidence map›Paper›PMID 40417720›Full record

SynthesisFrontiers in nuclear medicine2025

The role of FAPI PET/CT in patients with lymphoma: a systematic review.

Natale Quartuccio, Stefania Nicolosi, Sabina Pulizzi, Dante D'Oppido, Salvatore Ialuna

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natale QuartuccioNuclear Medicine Unit, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.
Stefania NicolosiNuclear Medicine Unit, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.
Sabina PulizziNuclear Medicine Unit, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.
Dante D'OppidoNuclear Medicine Unit, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.
Salvatore IalunaNuclear Medicine Unit, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fluorodeoxyglucose (FDG) PET/CT is typically the reference imaging method for assessing and tracking lymphomas. However, fibroblast activation protein inhibitor (FAPI) PET is being explored as a potentially useful option, especially when Fluorodeoxyglucose (FDG) scans do not show clear results. Methods: For this systematic review, two researchers searched PubMed/MEDLINE and Cochrane CENTRAL for studies on FAPI PET/CT in lymphoma patients. Results: The literature search initially retrieved 249 articles. After removing duplicates and screening titles and abstracts, and full text, there was a final selection of 15 articles (3 original studies and 12 case reports), encompassing a total of 270 patients. The three original studies were judged to have a low risk of bias according to the QUADAS-2 criteria. The systematic review reveals that FAPI PET/CT exhibits lower diagnostic sensitivity than [ Discussion: [

Indexed as

DLBCLFAPIFDGlymphomaNHLpositron emission tomographysystematic review

Identifiers

PMID40417720
PMCPMC12101064

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.