ArticleFrontiers in medicine2025
Development and validation of a nomogram for predicting low bone mineral density in male patients with ankylosing spondylitis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This retrospective cohort study aimed to develop and validate clinical nomogram models for predicting site-specific low bone mineral density (BMD) risk in male patients with ankylosing spondylitis (AS). Methods: This study enrolled male AS patients treated at the Rheumatology Department of Jiangsu Provincial Hospital of Traditional Chinese Medicine between January 2017 and September 2024. A total of 322 eligible patients were randomly allocated to training and validation cohorts at a 7:3 ratio. Potential predictors of low BMD at the lumbar spine (LS) and left hip (LH) were initially screened through univariate logistic regression ( Results: This study included 322 male AS patients randomly allocated to training ( Conclusion: This study developed clinical prediction models with excellent discriminative ability and substantial clinical utility for male patients with AS. These models offer rheumatologists an efficient tool to rapidly assess individual risks of low BMD, facilitating early diagnostic decision-making and enabling personalized interventions tailored to anatomical site-specific osteoporosis risks.
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