Evidence map›Paper›PMID 40417664›Full record

ArticleFrontiers in medicine2025

The microbiome in endometrial cancer: vaginal milieu matters.

Igor Govorov, Eduard Komlichenko, Elena Ulrikh, Elena Dikareva, Tatiana Pervunina, Oksana Vazhenina, Amina Dzharbaeva, Olga Kalinina, Ekaterina Zaikova, Zoia Razumova and 2 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Igor GovorovAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Eduard KomlichenkoAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Elena UlrikhAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Elena DikarevaAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Tatiana PervuninaAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Oksana VazheninaAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Amina DzharbaevaAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Olga KalininaAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Ekaterina ZaikovaAlmazov National Medical Research Centre, Saint-Petersburg, Russia.
Zoia RazumovaDivision of Obstetrics and Gynecology, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Miriam MintsDivision of Obstetrics and Gynecology, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Stanislav SitkinAlmazov National Medical Research Centre, Saint-Petersburg, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cancer remains one of the most common malignancies in women, and its incidence is particularly increasing in developed countries. Despite the well-known promotive role of excessive exposure to estrogen, many other details of the pathogenesis of endometrial cancer remain unknown. Recent studies have elucidated the emerging role of the resident microbiota in the progression of various diseases, including cancer. Next-generation sequencing demonstrated that the uterine cavity, previously considered sterile, contains a composition-rich microbiota. In this work, we determined the differences in the composition of the intrauterine microbiota between patients with endometrial cancer and its precursor-endometrial hyperplasia.

Indexed as

carcinogenesisendometrial cancerendometrial hyperplasiaendometrial microbiotamicrobiotavaginal microbiota

Identifiers

PMID40417664
PMCPMC12098060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.