Evidence map›Paper›PMID 40417585›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2024

Development of a Human Evaluation Framework and Correlation with Automated Metrics for Natural Language Generation of Medical Diagnoses.

Emma Croxford, Yanjun Gao, Brian Patterson, Daniel To, Samuel Tesch, Dmitriy Dligach, Anoop Mayampurath, Matthew M Churpek, Majid Afshar

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Validating LLM judges for automated oversight of patient communication.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. Article
  5. Toward digital twins in the intensive care unit: a medication management case study.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Emma CroxfordBiostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin Madison.
Yanjun GaoDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin Madison.
Brian PattersonDepartment of Emergency Medicine, School of Medicine and Public Health, University of Wisconsin Madison.
Daniel ToDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin Madison.
Samuel TeschDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin Madison.
Dmitriy DligachDepartment of Computer Science, Loyola University Chicago.
Anoop MayampurathBiostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin Madison.
Matthew M ChurpekDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin Madison.
Majid AfsharDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin Madison.

Funding

Research Training for Computation and Informatics in Biology and MedicineT15LM007359 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI Mark W. Craven, Colin Noel Dewey · 2002 to 2026
$22.6M
Learning Universal Patient Representations with Hierarchical TransformersR01LM012973 · NLM · BOSTON CHILDREN'S HOSPITAL · PI Timothy A Miller · 2019 to 2026
$3.5M
Developing and Evaluating Multi-Modal Clinical Diagnostic Reasoning Models for Automated Diagnosis GenerationK99LM014308 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI GAO, YANJUN · 2023 to 2023
$87k
NLM NIH HHS K99 LM014308NLM NIH HHS R01 LM012973NLM NIH HHS T15 LM007359
6 · The paper itself

Abstract

In the evolving landscape of clinical Natural Language Generation (NLG), assessing abstractive text quality remains challenging, as existing methods often overlook generative task complexities. This work aimed to examine the current state of automated evaluation metrics in NLG in healthcare. To have a robust and well-validated baseline with which to examine the alignment of these metrics, we created a comprehensive human evaluation framework. Employing ChatGPT-3.5-turbo generative output, we correlated human judgments with each metric. None of the metrics demonstrated high alignment; however, the SapBERT score-a Unified Medical Language System (UMLS)- showed the best results. This underscores the importance of incorporating domain-specific knowledge into evaluation efforts. Our work reveals the deficiency in quality evaluations for generated text and introduces our comprehensive human evaluation framework as a baseline. Future efforts should prioritize integrating medical knowledge databases to enhance the alignment of automated metrics, particularly focusing on refining the SapBERT score for improved assessments.

Indexed as

Natural Language ProcessingElectronic Health RecordsHumansUnified Medical Language System

Identifiers

PMID40417585
PMCPMC12099413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.