Evidence map›Paper›PMID 40417415›Full record

ArticleF&S reviews2025

In vivo gamete toxicology in the context of in vitro fertilization: a narrative review.

Morgan Orsolini, Jason Russack, Huey Huynh, Douglas Raburn, John Fox, Danny Schust

Abstract read
In one paragraph

Article in F&S reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Morgan OrsoliniDuke University, Department of Obstetrics and Gynecology, Durham, NC USA.
Jason RussackLifeAire Systems, Allentown, PA USA.
Huey HuynhLifeAire Systems, Allentown, PA USA.
Douglas RaburnDuke University, Department of Obstetrics and Gynecology, Durham, NC USA.
John FoxLehigh University, Department of Civil and Environmental Engineering Bethlehem, PA USA.
Danny SchustDuke University, Department of Obstetrics and Gynecology, Durham, NC USA.

Funding

Duke University Program in Environmental HealthT32ES021432 · NIEHS · DUKE UNIVERSITY · PI Akhenaton-Andrew Dhafir Jones, Joel Newman Meyer · 2013 to 2026
$4.0M
NIEHS NIH HHS T32 ES021432
6 · The paper itself

Abstract

IVF as a clinical method to surmount infertility has existed since the 1970s, and yet fertilization, embryo development, pregnancy, and live birth rates remain unacceptably low. Although a multitude of factors may contribute to stagnated success despite substantial advances in basic and applied IVF sciences, gamete quality is inarguably integral to IVF success rates. In this review, the authors will explore the role of environmental toxicology in impairing

Indexed as

embryoenvironmentinfertilityIVFtoxicology

Identifiers

PMID40417415
PMCPMC12097544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.