Evidence map›Paper›PMID 40417298›Full record

ArticleChemical science2025

Bio-inspired total synthesis of daphnepapytone A.

Joan Pereira, Nicolas Casaretto, Gilles Frison, Bastien Nay

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Studies toward the Caged Sesquiterpenoid Daphnepapytone A.The Journal of organic chemistry · 2026
    Article
  2. Article
  3. Total Synthesis of Daphnepapytone A.The Journal of organic chemistry · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joan PereiraLaboratoire de Synthèse Organique, Ecole Polytechnique, ENSTA Paris, CNRS, Institut Polytechnique de Paris Route de Saclay F-91128 Palaiseau Cedex France bastien.nay@polytechnique.edu.ORCID https://orcid.org/0009-0002-4667-5065
Nicolas CasarettoLaboratoire de Chimie Moléculaire, Ecole Polytechnique, ENSTA Paris, CNRS, Institut Polytechnique de Paris Route de Saclay F-91128 Palaiseau Cedex France.ORCID https://orcid.org/0000-0003-0636-983X
Gilles FrisonLaboratoire de Chimie Théorique, Sorbonne Université, CNRS F-75005 Paris France.ORCID https://orcid.org/0000-0002-5677-3569
Bastien NayLaboratoire de Synthèse Organique, Ecole Polytechnique, ENSTA Paris, CNRS, Institut Polytechnique de Paris Route de Saclay F-91128 Palaiseau Cedex France bastien.nay@polytechnique.edu.ORCID https://orcid.org/0000-0002-1209-1830

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Daphnepapytone A (1) is an unprecedented guaiane-derived sesquiterpene characterized by a bridged and highly substituted cyclobutane. We describe its total synthesis through a bio-inspired sequence of skeleton construction and late-stage oxidation. After the Eschenmoser-Tanabe fragmentation of (

Identifiers

PMID40417298
PMCPMC12096516

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.