Evidence map›Paper›PMID 40417247›Full record

ArticleMarine life science & technology2025

Penicipyrrolidines A-N, pyrrolidine derivatives with inhibitory effects on EMT and fibroblast activation from the mangrove-derived fungus

Li-Ming He, Xuan Deng, Li-Hua Ni, Shi-Qi Cai, Jinhu Chen, Zejin Liao, Mengke Zhang, Hua Shui, Kong-Kai Zhu, Song Wu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine life science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Li-Ming He *Department of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Xuan Deng *Department of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Li-Hua Ni *Department of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Shi-Qi CaiDepartment of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Jinhu ChenDepartment of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Zejin LiaoDepartment of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Mengke ZhangDepartment of Pharmacy, Renmin Hospital of Wuhan University, Wuhan, 430060 China.
Hua ShuiDepartment of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Kong-Kai ZhuAdvanced Medical Research Institute, Shandong University, Jinan, 250012 China.
Song WuKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Ping GaoDepartment of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Ariel M SarottiFacultad de Ciencias Bioquímicas y Farmaceuticas, Instituto de Química Rosario (CONICET), Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina.
Kui HongKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
Xiao-Yan WuDepartment of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.
You-Sheng CaiDepartment of Nephrology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An investigation of the mangrove-derived fungus Supplementary Information: The online version contains supplementary material available at 10.1007/s42995-025-00282-0.

Indexed as

Fibroblast activationPenicillium sp.PyrrolidinePyrrolizidine alkaloidsRenal fibrosis

Identifiers

PMID40417247
PMCPMC12102406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.