Evidence map›Paper›PMID 40417138›Full record

ArticleEnvironmental science : water research & technology2025

Removal of psychopharmaceuticals from WWTP effluent by an algae-mussel trophic cascade: a potential nature-based solution?

Charlie J E Davey, Tom V van der Meer, Thomas L Ter Laak, Piet F M Verdonschot, Michiel H S Kraak

Abstract read
In one paragraph

Article in Environmental science : water research & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Charlie J E DaveyInstitute for Biodiversity and Ecosystem Dynamics, University of Amsterdam Amsterdam The Netherlands c.j.e.davey@uva.nl.ORCID https://orcid.org/0000-0002-2436-9369
Tom V van der MeerInstitute for Biodiversity and Ecosystem Dynamics, University of Amsterdam Amsterdam The Netherlands c.j.e.davey@uva.nl.
Thomas L Ter LaakInstitute for Biodiversity and Ecosystem Dynamics, University of Amsterdam Amsterdam The Netherlands c.j.e.davey@uva.nl.
Piet F M VerdonschotWageningen Environmental Research Wageningen UR P.O. Box 47 6700 AA Wageningen The Netherlands.ORCID https://orcid.org/0000-0002-4126-7452
Michiel H S KraakInstitute for Biodiversity and Ecosystem Dynamics, University of Amsterdam Amsterdam The Netherlands c.j.e.davey@uva.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychopharmaceuticals are an emerging group of hazardous contaminants that pose a risk to the aquatic environment. Yet, modern wastewater treatment plants (WWTPs) do not remove them sufficiently to alleviate these risks. The present study aimed therefore to explore the effectiveness of an alternative nature-based tertiary treatment of WWTP effluent to remove psychopharmaceuticals. To this end, an algae-mussel trophic cascade setup was designed in which algae were grown in effluent over the course of 11 days and subsequently fed to mussels for a further 3 days. Removal of 30 psychopharmaceuticals for each of the treatments (algae, mussels, algae + mussels) was calculated relative to control samples, and removal efficiency was contextualised by performing an indicative risk assessment. Twelve psychopharmaceuticals were quantified during the experiment, with 11 encountered in all treatments. The compounds fell into 3 categories: positive removal (citalopram, lamotrigine, and venlafaxine), negative removal (carbamazepine, gabapentin, and pregabalin), and no significant changes in concentration (amitriptyline, quetiapine, tramadol, fluvoxamine, lidocaine, and ibuprofen). Both positive and negative removals were largely driven by the presence of the algae rather than that of the mussels. Compounds with a low p

Identifiers

PMID40417138
PMCPMC12096836

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.