Evidence map›Paper›PMID 40416904›Full record

ArticleCureus2025

Unexpected Development of Pericardial Effusion in a Patient With Influenza and Secondary Bacterial Infection.

Pooriya Bahadoran, Daniel Echeverria, Hansani Angammana, Redi Nikollari, Lisa N Glass

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pooriya BahadoranMedicine, St. Barnabas Hospital Health System, Bronx, USA.
Daniel EcheverriaMedicine, St. Barnabas Hospital Health System, Bronx, USA.
Hansani AngammanaInternal Medicine, St. Barnabas Hospital Health System, Bronx, USA.
Redi NikollariMedicine, St. Barnabas Hospital Health System, Bronx, USA.
Lisa N GlassPulmonary and Critical Care Medicine, St. Barnabas Hospital Health System, Bronx, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza poses a significant burden on healthcare systems worldwide, particularly when complicated by bacterial coinfections. Such cases often require intensive medical management. We present the case of a previously healthy young man whose influenza infection was complicated by bacterial coinfection, necessitating complex therapeutic intervention. During treatment with intrapleural fibrinolytic therapy, the patient was found to have developed a large pericardial effusion. While a causal relationship cannot be definitively established, this temporal association raises concern for a potential, previously unreported complication. We present this case to raise clinical awareness of this life-threatening possibility and encourage its consideration in the differential diagnosis when managing similar patients.

Indexed as

alteplaseempyemafibrinolytic-associated adverse eventsintrapleural complicationsintrapleural fibrinolytic therapypericardial effusionpericarditispleural infection

Identifiers

PMID40416904
PMCPMC12103259

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.