Evidence map›Paper›PMID 40416893›Full record

ArticleAnnals of burns and fire disasters2025

Upper gastrointestinal bleeding in severely burned patients: incidence, risk factors and outcome.

B Tlili, H Fredj, A Mokline, H Galai, S Zarouk, B Gasri, I Jemi, A A Messadi

Abstract read
In one paragraph

Article in Annals of burns and fire disasters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

B TliliMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.
H FredjMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.
A MoklineMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.
H GalaiMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.
S ZaroukMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.
B GasriMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.
I JemiMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.
A A MessadiMajor Burns ICU, Center for Traumatology and Major Burns, Ben Arous, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upper gastrointestinal bleeding (UGIB) is a rare complication of the ICU stay. Our objective was to study the epidemiological, clinical manifestations, and evolutionary characteristics of UGIB, and identify its risk factors in severely burned patients. This is a retrospective case-control study of burned patients in the ICU in Tunisia over a period of 6 years, including all adult patients with severe burns who presented at least one episode of gastrointestinal bleeding. The control group consisted of severely burned patients with no gastrointestinal bleeding during their ICU stay. The two groups were matched according to age, gender and extent of burns. The incidence of gastrointestinal bleeding was 2.3% with an average time of onset of 19±17 days. Esophagogastroduodenoscopy was performed in 45 patients showing bulbar ulcer, gastric ulcer, and oesophageal ulcerations in respectively 28, 8 and 3 patients. In the multivariate study, acute kidney injury (OR 13.8, CI [2.9-67], p=0.001), fluid intake <2 ml/kg/%TBSA over the first 24h (OR 10, IC [1.5-68.5], p=0.019), and length of ICU stay >10 days (OR 48.2, IC [4.4-530], p=0.002) were independent risk factors for the occurrence of gastrointestinal bleeding. Mortality in the UGIB group was higher (55.8% vs 25%, p=0.001). Upper gastrointestinal bleeding is a serious complication of a burn patient's ICU stay. Acute renal failure, low fluid intake in the first 24h, and a long duration of ICU stay were independent risk factors for its occurrence.

Indexed as

burnscomplicationsgastrointestinal haemorrhagerisk factors

Identifiers

PMID40416893
PMCPMC12097495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.