Evidence map›Paper›PMID 40416790›Full record

ArticleJID innovations : skin science from molecules to population health2025

SUB6 Subtilisin is Involved During the Initial Adhesion of

Émilie Faway, Wilfried Poirier, Tsuyoshi Yamada, Kiyotaka Ozawa, Michel Monod, Bernard Mignon, Yves Poumay

Abstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Dermatophytosis: An Update on Global Epidemiology.Journal of fungi (Basel, Switzerland) · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Émilie FawayMolecular Physiology Research Unit, NAmur Research Institute for Life Sciences (URPHYMNARILIS), Faculty of Medicine, University of Namur, Namur, Belgium.
Wilfried PoirierFundamental and Applied Research for Animals & Health (FARAH), Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.
Tsuyoshi YamadaTeikyo University Institute of Medical Mycology, Teikyo University, Tokyo, Japan.
Kiyotaka OzawaTeikyo University Institute of Medical Mycology, Teikyo University, Tokyo, Japan.
Michel MonodDepartment of Dermatology, Centre Hospitalier Universitaire Vaudios, Lausanne, Switzerland.
Bernard MignonFundamental and Applied Research for Animals & Health (FARAH), Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.
Yves PoumayMolecular Physiology Research Unit, NAmur Research Institute for Life Sciences (URPHYMNARILIS), Faculty of Medicine, University of Namur, Namur, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing incidence of dermatophytoses and the emergence of strains resistant to available antifungal agents raise the need for a better understanding of the virulence mechanisms of dermatophytes to identify new therapeutic targets. The proteases of the subtilisin family have previously been highlighted as potential virulence factors for dermatophytes, in particular the protease SUB6, which was first discovered to be an allergen capable of inducing immediate and delayed hypersensitivity skin reactions. Moreover,

Indexed as

AdhesionDermatophytosisReconstructed human epidermisSubtilisinVirulence factor

Identifiers

PMID40416790
PMCPMC12099874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.