ArticleFrontiers in public health2025
A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Reproductive Complication in Rhesus Macaques (Macaca mulatta): Prevalence, Risk Factors, and Successful Surgical Resolution of Vaginal Prolapse Postpartum.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Global, Regional, and National Burden and Trends of Pelvic Organ Prolapse Among Women of Childbearing Age and Projected Trends to 2041 Using ARIMA Models: A Systematic Study Based on the GBD from 1990 to 2021.International journal of women's health · 2026Article
- Pelvic Organ Prolapse: Current Challenges and Future Perspectives.Journal of clinical medicine · 2025Review
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Authors and funding
5 authors.
Funding
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Abstract
Background: Pelvic organ prolapse (POP) is a prevalent condition affecting millions of women globally. Understanding its temporal trends and regional disparities is essential for effective public health interventions. Methods: A cross-sectional analysis was conducted using data from the Global Burden of Disease (GBD) study, examining trends in POP incidence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021. We analyzed the estimated annual percentage change (EAPC) and explored the association with the socio-demographic index (SDI). Results: From 1990 to 2021, global POP cases increased from approximately 8.4 million to 14.0 million, while the age-standardized incidence rate (ASIR) declined from 374.84 to 317.51 per 100,000 population (EAPC = -0.46). Deaths rose from 281 to 486, but the age-standardized death rate (ASDR) remained stable. DALYs increased from 232,432 to 389,358, with a decrease in age-standardized DALY rate (EAPC = -0.59). Low-SDI regions exhibited the highest ASIR, ASDR, and DALYs in 2021. Conclusion: The global burden of pelvic organ prolapse has increased in absolute numbers, although age-standardized rates have declined. Low-SDI regions continue to face the highest burden, highlighting the need for targeted healthcare interventions.
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