Evidence map›Paper›PMID 40416617›Full record

ArticlePeerJ2025

Antifungal activity and mechanism of novel peptide

Ruxia Cai, Na Zhao, Chaoqin Sun, Mingjiao Huang, Zhenlong Jiao, Jian Peng, Jin Zhang, Guo Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruxia Cai *School of Basic Medical Sciences, Guizhou Key Laboratory of Microbial and Infectious Disease Prevention & Control, Guizhou Medical University, Guiyang, Guizhou, China.
Na Zhao *School of Basic Medical Sciences, Guizhou Key Laboratory of Microbial and Infectious Disease Prevention & Control, Guizhou Medical University, Guiyang, Guizhou, China.
Chaoqin SunSchool of Basic Medical Sciences, Guizhou Key Laboratory of Microbial and Infectious Disease Prevention & Control, Guizhou Medical University, Guiyang, Guizhou, China.
Mingjiao HuangSchool of Basic Medical Sciences, Guizhou Key Laboratory of Microbial and Infectious Disease Prevention & Control, Guizhou Medical University, Guiyang, Guizhou, China.
Zhenlong JiaoSchool of Basic Medical Sciences, Guizhou Key Laboratory of Microbial and Infectious Disease Prevention & Control, Guizhou Medical University, Guiyang, Guizhou, China.
Jian PengSchool of Basic Medical Sciences, Guizhou Key Laboratory of Microbial and Infectious Disease Prevention & Control, Guizhou Medical University, Guiyang, Guizhou, China.
Jin ZhangSchool of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Guo GuoSchool of Basic Medical Sciences, Guizhou Key Laboratory of Microbial and Infectious Disease Prevention & Control, Guizhou Medical University, Guiyang, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is a pressing need to create innovative alternative treatment approaches considering the overuse of antifungal drugs causes the number of clinically isolated fluconazole-resistant Methods: The study aimed to comprehensively investigate the antimicrobial activity and mechanisms of GmAMP against fluconazole-resistant Results: GmAMP exhibited significant antifungal activity against fluconazole-resistant Conclusion: GmAMP can disrupt the cell membrane of fluconazole-resistant

Indexed as

Antifungal AgentsAntimicrobial PeptidesCandida tropicalisDrug Resistance, FungalFluconazoleAnimalsBiofilmsMicrobial Sensitivity TestsMothsReactive Oxygen SpeciesAntifungal AgentsAntimicrobial PeptidesFluconazoleReactive Oxygen SpeciesAntifungal activityAntimicrobial peptideCandida tropicalisDrug-resistanceGmAMP

Identifiers

PMID40416617
PMCPMC12101439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.