ArticleSensors and actuators. B, Chemical2025
High-Precision Micro-Total Analysis of Sodium Ions in Breast Milk.
Article in Sensors and actuators. B, Chemical, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Advances in optical and electrochemical aptasensors for tumor biomarker alpha-fetoprotein.Mikrochimica acta · 2026Review
- Wearable sensors: in situ detection tools for plant physiological markers and growth environment information.Mikrochimica acta · 2025Review
- Selective peroxidase-like activity of ferroelectric BiFeOMikrochimica acta · 2025Article
- Electrochemical detection of cardiovascular diseases and treatment platform based on microfluidic technology.Mikrochimica acta · 2025Review
- Rapid Microfluidic Ion-Exchange Optode System for Point-of-Care Determination of Sodium Concentration in Serum.Biosensors · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Measuring sodium ion concentration in breast milk can provide crucial health information for both mother and infant, including early signs of low-grade infection and reduced milk supply. Traditional sensing methods are slow, bulky, expensive, and require skilled operators. Here, we develop a coverslip-sized, high-precision lab-on-a-chip device that processes and detects sodium ions in human breast milk. The device uses micro-electrodialysis to extract sodium ions into a simple acceptor solution with 92 ± 3% efficiency and employs a graphene ion-selective sensor for high-performance quantification. We demonstrate a straightforward calibration strategy, enabling the device to measure breast-milk sodium ion levels in 141 seconds, with accuracy comparable to inductively coupled plasma mass spectrometry. Our approach offers a promising pathway to efficient, point-of-care diagnosis of conditions associated with metal-ion levels in complex liquid-biopsy samples.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.