Evidence map›Paper›PMID 40416324›Full record

ArticleACS photonics2025

Enhanced Interferometric Imaging by Rotating Coherent Scattering Microscopy.

Kishwar Iqbal, Jan Christoph Thiele, Emanuel Pfitzner, Philipp Kukura

Abstract read
In one paragraph

Article in ACS photonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kishwar IqbalThe Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford OX1 3QU, U.K.ORCID https://orcid.org/0009-0001-7081-4347
Jan Christoph ThieleThe Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford OX1 3QU, U.K.ORCID https://orcid.org/0000-0002-6638-6298
Emanuel PfitznerThe Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford OX1 3QU, U.K.
Philipp KukuraThe Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford OX1 3QU, U.K.ORCID https://orcid.org/0000-0003-0136-7704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Label-free microscopy on the nanoscale requires high-sensitivity imaging. The challenge of visualizing very small objects, such as nanoparticles, arises from their weak interaction with light. As a result, a combination of high signal-to-noise ratio imaging and background rejection is needed for detection and quantification. Here, we combine concepts from interferometric scattering (iSCAT) microscopy and rotating coherent scattering (ROCS) microscopy to optimize both background rejection and high-sensitivity imaging. Total internal reflection produces a background light intensity more than 2 orders of magnitude stronger than in iSCAT. Despite this, we successfully image 20 nm gold nanoparticles using our combined approach while achieving a signal-to-noise ratio (SNR) comparable to iSCAT at incident power densities as low as 0.04 kW/cm

Indexed as

evanescent fieldgold nanoparticleinterference microscopyinterferometric scattering microscopyoptical contrastrotating coherent scattering

Identifiers

PMID40416324
PMCPMC12100722

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.