Evidence map›Paper›PMID 40416314›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Imaging flow cytometry: from high - resolution morphological imaging to innovation in high - throughput multidimensional biomedical analysis.

Qing Huang, Zhengyu Zhou, Qiao Lv, Qian Min, Lu Jiang, Qian Chen, Jin Peng, Hongli Zhou, Ju Zhou, Qian Dai and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qing Huang *Clinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Zhengyu Zhou *Department of Epidemic Prevention, 92914 Hospital, Hainan, China.
Qiao LvClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Qian MinClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Lu JiangClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Qian ChenClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Jin PengClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Hongli ZhouClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Ju ZhouClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Qian DaiClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.
Jianyun ZhouClinical Medical Research Center, Xinqiao Hospital, Army Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging flow cytometry (IFC), as an extension of conventional flow cytometry, has emerged as a cutting-edge cellular analysis tool by integrating high-resolution imaging technology, and has shown significant potential and application value in biomedical research. In this paper, we comprehensively review the evolution of IFC from its early theoretical development to its current mature application, and explain its working principle, unique advantages, and the current status of its application in several biomedical fields. The paper focuses on how IFC integrates high-throughput and morphological imaging, highlighting its key role in cell biology, immunology, oncology, and environmental monitoring. Furthermore, the paper addresses the challenges and opportunities in data analysis, and proposes the potential of artificial intelligence (AI) and machine learning technologies to drive its progress. The paper concludes with an outlook on the future of IFC, predicting its application in emerging research areas and emphasizing the role of continuous technological innovation in driving the development of the field. It aims to provide researchers with a comprehensive view of IFC to promote its widespread application in biomedical research.

Indexed as

artificial intelligencebiomedical researchhigh - throughput analysisimaging flow cytometrymachine learningmorphological imaging

Identifiers

PMID40416314
PMCPMC12098090

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.