Evidence map›Paper›PMID 40416276›Full record

ArticleCureus2025

Epidemiology and Outcomes of Intramedullary Nailing for Tibial Diaphyseal Fractures: A Retrospective Multicenter Cohort Study.

Fábio Lucas Rodrigues, Ana Lya Moya Ferrari, Fernando Ferraz Faria, Rafael Luiz Emmanoel Pinto, Manuela Fernandes Lopes, Maria Eduarda Alencar Santos, Evelyn Cardenas Varela, Manuel Jucelino Lopes Filho, Marianna Nogueira Cecyn, Nelson Henrique Carvalho De Oliveira

Registry-linked trialAbstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07554079 (Standard Versus Short Course Prophylactic Antibiotic in Femur and Tibia Shaft Fractures Managed With Intramedullary Interlocking Nail), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07554079 nacompletednot on this map

Standard Versus Short Course Prophylactic Antibiotic in Femur and Tibia Shaft Fractures Managed With Intramedullary Interlocking Nail: A Prospective Randomized Comparative Study Using the ASEPSIS Score

TypeinterventionalSponsorKathmandu University School of Medical SciencesRan2024 to 2025Enrolled56ConditionsFracture Femur, Fracture Tibia, Surgical Site Infection (SSI), AntibioticArmsShort Course Antibiotics, Standard Course Antibiotics
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Interface stability of intramedullary nail locking configurations under combined axial and torsional loading.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fábio Lucas RodriguesOrthopedics and Traumatology, Santo André, São Bernardo do Campo, and São Caetano do Sul (ABC) Medical School, Santo André, BRA.
Ana Lya Moya FerrariResearch and Development, Biomecanica, Jaú, BRA.
Fernando Ferraz FariaOrthopedics and Traumatology, Cajuru University Hospital, Curitiba, BRA.
Rafael Luiz Emmanoel PintoOrthopedics and Traumatology, Cajuru University Hospital, Curitiba, BRA.
Manuela Fernandes LopesOrthopedics and Traumatology, Adriano Jorge Hospital Foundation, Manaus, BRA.
Maria Eduarda Alencar SantosOrthopedics and Traumatology, Adriano Jorge Hospital Foundation, Manaus, BRA.
Evelyn Cardenas VarelaOrthopedics and Traumatology, Adriano Jorge Hospital Foundation, Manaus, BRA.
Manuel Jucelino Lopes FilhoOrthopedics and Traumatology, Adriano Jorge Hospital Foundation, Manaus, BRA.
Marianna Nogueira CecynPsychobiology, Federal University of São Paulo, São Paulo, BRA.
Nelson Henrique Carvalho De OliveiraOrthopedics and Traumatology, Adriano Jorge Hospital Foundation, Manaus, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntramedullary nails (IMN) are frequently used to fix tibial diaphyseal fractures. Despite good outcomes, complications such as infections, malunion, and nonunion may still occur, especially in low- and middle-income countries where healthcare resources and trauma care systems are often limited. This retrospective multicenter cohort study aimed to evaluate the epidemiology and clinical outcomes of IMN in tibial diaphyseal fractures in Brazil in terms of consolidation and complications. MATERIALS AND

methodsWe analyzed data from 125 patients who underwent IMN for fixation of tibial diaphyseal fractures between August 2020 and January 2024 at two Brazilian hospitals.

resultsTraffic accidents were the most common injury mechanism (84%), and closed fractures accounted for 80.8% of the cases. Most patients (98.4%) achieved fracture consolidation within six months post-surgery, with a low complication rate (3.2%), including two nonunions with screw breakage, one malunion, and one infection. There was a significant association between previous external fixation and the type of fracture (closed and open). However, there was no significant association between previous external fixation and consolidation one year post-surgery.

conclusionThe findings suggest that IMN is effective in achieving consolidation and low complication rates in Brazilian hospitals.

Indexed as

consolidationintramedullary fracture fixationnailshaft fracturestibial fractures

Identifiers

PMID40416276
PMCPMC12102775

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.