ArticleCureus2025
Unveiling the Rare: A Case Report of Rectal Schwannoma in a Neurofibromatosis Type 1 Patient.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Neurofibromatosis type 1 (NF-1) is an autosomal dominant neurocutaneous disorder characterized by skin abnormalities, such as café-au-lait macules and skinfold freckling, as well as peripheral nerve sheath tumors such as neurofibromas, schwannomas, and various other tumors. A 28-year-old man with a history of NF-1 presented to our facility with rectal bleeding. A rectal mass was subsequently discovered on colonoscopy and subsequent imaging. This mass was biopsied with histopathology consistent with a low-grade schwannoma. Schwannomas, while less common in NF-1 than NF-2, do sometimes occur in NF-1 patients, most commonly along the cranial, spinal, or peripheral nerves. These tumors also rarely occur in the gastrointestinal tract and even more rarely within the rectum specifically. Schwannoma must be considered in the differential for any rectal mass discovered in a patient with NF-1, so that the patient can be appropriately managed and treated.
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