Evidence map›Paper›PMID 40416191›Full record

ArticleCureus2025

Pathological Clavicular Fracture Following Brachial Plexopathy Occurring Over 50 Years After Radiation Therapy: A Case Report.

Toshio Netsu, Masato Tsuchiya, Satoshi Kubo, Ryuichi Azuma

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Toshio NetsuDepartment of Plastic and Reconstructive Surgery, National Defense Medical College, Tokorozawa, JPN.
Masato TsuchiyaDepartment of Plastic and Reconstructive Surgery, National Defense Medical College, Tokorozawa, JPN.
Satoshi KuboDepartment of Plastic and Reconstructive Surgery, National Defense Medical College, Tokorozawa, JPN.
Ryuichi AzumaDepartment of Plastic and Reconstructive Surgery, National Defense Medical College, Tokorozawa, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy is a common cancer treatment that may cause long-term complications such as bone and neurological disorders. This study presents a pathological clavicular fracture that occurred 50 years after radiotherapy for a sarcoma. A 67-year-old female with a history of radiation therapy following surgery at the age of 10 years developed a clavicular fracture without trauma. Prior to the fracture, the patient experienced progressive brachial plexopathy over the past 15 years. Biopsy revealed no malignancy, which led to the diagnosis of a pathological fracture. This study illustrates the delayed onset of radiation-induced complications, with neurological damage appearing earlier than the fracture. Moreover, it underscores the importance of considering radiation-induced bone fragility in patients with unexplained fractures, particularly individuals with prior radiation exposure. Early detection of neurological damage, such as brachial plexopathy, may offer an opportunity for preventive care. Furthermore, it highlights the necessity of patient education regarding the long-term effects of radiation therapy, including bone fragility and the risk of pathological fractures.

Indexed as

late-onset radiation complicationslong-term cancer survivorshiposteoradionecrosispathological clavicle fractureradiation-induced brachial plexopathyradiation therapysarcoma

Identifiers

PMID40416191
PMCPMC12103087

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.