Evidence map›Paper›PMID 40416066›Full record

ReviewCraniomaxillofacial trauma & reconstruction2025

Redefining and Identifying Evidence-Based Indications for Open Reduction and Internal Fixation in Mandibular Condylar Fractures: A Comprehensive Systematic Review and Evidence Analysis.

Stephen A L Y Youssef, Iva I Raghoebar, Renee Helmers, Jan de Lange, Leander Dubois

Abstract readReview
In one paragraph

Review in Craniomaxillofacial trauma & reconstruction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephen A L Y YoussefDepartment of Oral and Maxillofacial Surgery, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; i.i.raghoebar@amsterdamumc.nl (I.I.R.); r.helmers@amsterdamumc.nl (R.H.); j.delange@amsterdamumc.nl (J.d.L.); l.dubois@amsterdamumc.nl (L.D.).
Iva I RaghoebarDepartment of Oral and Maxillofacial Surgery, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; i.i.raghoebar@amsterdamumc.nl (I.I.R.); r.helmers@amsterdamumc.nl (R.H.); j.delange@amsterdamumc.nl (J.d.L.); l.dubois@amsterdamumc.nl (L.D.).ORCID https://orcid.org/0000-0001-6260-7332
Renee HelmersDepartment of Oral and Maxillofacial Surgery, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; i.i.raghoebar@amsterdamumc.nl (I.I.R.); r.helmers@amsterdamumc.nl (R.H.); j.delange@amsterdamumc.nl (J.d.L.); l.dubois@amsterdamumc.nl (L.D.).
Jan de LangeDepartment of Oral and Maxillofacial Surgery, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; i.i.raghoebar@amsterdamumc.nl (I.I.R.); r.helmers@amsterdamumc.nl (R.H.); j.delange@amsterdamumc.nl (J.d.L.); l.dubois@amsterdamumc.nl (L.D.).ORCID https://orcid.org/0000-0003-0096-8217
Leander DuboisDepartment of Oral and Maxillofacial Surgery, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; i.i.raghoebar@amsterdamumc.nl (I.I.R.); r.helmers@amsterdamumc.nl (R.H.); j.delange@amsterdamumc.nl (J.d.L.); l.dubois@amsterdamumc.nl (L.D.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major controversy in maxillofacial surgery practice is the management of mandibular condylar fractures (CFs). The debate revolves around open versus closed treatment, rather than identifying clear indications whereby open reduction and internal fixation (ORIF) is the most viable treatment modality. Opinions regarding precise indications for ORIF remain unclear and non-uniform. We aimed to refocus the debate regarding the optimal treatment for CFs by identifying the recent indications for ORIF in the literature and assessing the quality of the existing evidence for each indication. This systematic review searched Medline, Embase and the Cochrane Central Register of Controlled Trials for eligible studies. The included studies consisted of articles from the past 15 years involving patients with any type of CF who underwent ORIF based on specified indications. From 4711 papers, 100 studies were included. In these, 121 indications were identified. The most cited indications for ORIF were those proposed by Zide and Kent, namely displacement/angulation ≥10° and ramus height shortening of ≥2 mm. Evidence supporting these indications is weak, relying mainly on expert opinion rather than robust data, with a focus on treatment comparisons. Clear, evidence-based cutoffs regarding when ORIF is the only viable treatment option are needed for a consensus.

Indexed as

evidence analysisindicationmandibular condyle fractureopen reduction and internal fixationopen treatmentsurgical treatment

Identifiers

PMID40416066
PMCPMC12101279

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.