Evidence map›Paper›PMID 40415887›Full record

ReviewFrontiers in neuroscience2025

The sneeze reflex in physiological and pathological states: a mini review.

Yang Rui, Tianyuan Xin, Yu Chen, Beiyi Xiang, Changwen Chen, Rong Dong, Zhe Chen

Abstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yang RuiLaboratory of Cough, Kunshan Key Laboratory of Chronic Cough, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, China.
Tianyuan XinLaboratory of Cough, Kunshan Key Laboratory of Chronic Cough, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, China.
Yu ChenLaboratory of Cough, Kunshan Key Laboratory of Chronic Cough, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, China.
Beiyi XiangLaboratory of Cough, Kunshan Key Laboratory of Chronic Cough, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, China.
Changwen ChenLaboratory of Cough, Kunshan Key Laboratory of Chronic Cough, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, China.
Rong DongDepartment of Physiology and Pharmacology, Southeast University, Nanjing, China.
Zhe ChenLaboratory of Cough, Kunshan Key Laboratory of Chronic Cough, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sneeze reflex serves as a protective response of the human body to environmental stimuli, with its regulatory mechanism largely depending on a complex nervous system. Current research indicates that the sneeze reflex can be triggered by both internal and external stimuli, including light and temperature. The composition of its reflex arc involves the coordinated action of multiple neural structures. Recent in-depth studies on the mechanism of the sneeze reflex have revealed a growing association between this reflex and various diseases, such as allergic rhinitis and infectious diseases. However, existing research primarily focuses on elucidating the neurophysiological basis of the sneeze reflex and its related neural pathways. The manifestations and mechanisms of the sneeze reflex under different pathological states remain underexplored, thereby limiting the potential application of the sneeze reflex in clinical diagnosis and treatment. This review aims to discuss the physiological mechanisms and pathological manifestations associated with the sneeze reflex.

Indexed as

central regulationcoughinnervationpathological manifestationssneeze reflex

Identifiers

PMID40415887
PMCPMC12098519

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.