Evidence map›Paper›PMID 40415842›Full record

ArticleACS omega2025

Antifungal Effect of Poly(methyl methacrylate) Coated with Polyelectrolyte Multilayers.

Klemen Bohinc, Anamarija Zore, Tina Velikonja, Franc Rojko, Roman Štukelj, Aleksander Učakar, Anže Abram, Nives Matijaković Mlinarić, Miha Čekada, Juraj Nikolić and 1 more

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Polymers · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Klemen BohincFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID https://orcid.org/0000-0003-2126-8762
Anamarija ZoreFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.
Tina VelikonjaFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.
Franc RojkoFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.
Roman ŠtukeljFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.
Aleksander UčakarJožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.
Anže AbramJožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.
Nives Matijaković MlinarićFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID https://orcid.org/0000-0002-3751-1790
Miha ČekadaJožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.
Juraj NikolićDepartment of Chemistry, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia.ORCID https://orcid.org/0000-0002-0548-4185
Davor KovačevićDepartment of Chemistry, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to teeth loss, a large proportion of the elderly rely on full or partial dentures for esthetic, speaking, and eating reasons. A variety of polymers are used in the production of removable prostheses, with poly-(methyl methacrylate) (PMMA) being a widely used material for making denture bases. However, underdenture stomatitis caused by the fungi Candida albicans is still an open problem. The purpose of this work was to consider the impact of polyelectrolyte multilayer (PEM) coating on PMMA surfaces and the effect of the addition of sucrose on the adhesion properties of C. albicans. Two polyelectrolytes were applied for the formation of the PEM coating: poly-(allylamine) hydrochloride (PAH) and poly-(acrylic) acid (PAA). The uncoated and coated surfaces were characterized in terms of topography, surface potential, and hydrophobicity. The extent of adhesion of C. albicans to the surfaces was assessed by scanning electron microscopy. Results show that surfaces coated with negatively charged PAA as the PEM terminating layer adhere less C. albicans than uncoated PMMA or surfaces coated with positively charged PAH as the PEM terminating layer. The addition of sucrose increases the fungal adhesion extent of C. albicans to both types of coated surfaces, lowering the PAA antiadhesion properties. With the addition of sucrose, we were trying to mimic the impact of dentures on patients with a sugar-rich diet.

Identifiers

PMID40415842
PMCPMC12096253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.