Evidence map›Paper›PMID 40415577›Full record

ArticleEuropean heart journal2025

Finerenone effects on biomarkers: an analysis from the FIGARO-DKD trial.

Mario Berger, Aidan MacNamara, João Pedro Ferreira, Peter Kolkhof, Sebastian Voss, Adam Skubala, Andrea Scalise, Laura Goea, Richard Nkulikiyinka, Bertram Pitt and 5 more

Abstract read
In one paragraph

Article in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Integrated morphological and transcriptomic analysis of bone disorders in aldosterone-salt hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  3. Article
  4. Review
  5. Diabetic kidney disease, biomarkers, and finerenone.Diabetes, obesity & metabolism · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mario BergerBayer AG, Pharmaceuticals, R&D, Wuppertal/Berlin, Germany.ORCID 0000-0002-9048-3928
Aidan MacNamaraBayer AG, Pharmaceuticals, R&D, Wuppertal/Berlin, Germany.ORCID 0000-0001-5958-2429
João Pedro FerreiraDepartment of Surgery and Physiology, Faculty of Medicine of the University of Porto, Cardiovascular Research and Development Center (UnIC@RISE), Porto, Portugal.ORCID 0000-0003-2422-4730
Peter KolkhofBayer AG, Pharmaceuticals, R&D, Wuppertal/Berlin, Germany.ORCID 0000-0003-3425-7528
Sebastian VossChrestos GmbH, Biomarker Statistics and Data Science Department, Essen, Germany.ORCID 0009-0000-0891-1747
Adam SkubalaBayer AG, Pharmaceuticals, R&D, Wuppertal/Berlin, Germany.ORCID 0009-0000-0496-5713
Andrea ScaliseBayer Hispania, S.L., Clinical Development, Barcelona, Spain.ORCID 0000-0002-9367-5773
Laura GoeaBayer AG, Pharmaceuticals, R&D, Wuppertal/Berlin, Germany.ORCID 0000-0003-0473-2885
Richard NkulikiyinkaBayer AG, Pharmaceuticals, R&D, Wuppertal/Berlin, Germany.ORCID 0009-0005-2145-7231
Bertram PittDepartment of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA.ORCID 0000-0001-5880-275X
Joachim Hanno IxDepartment of Medicine, University of California San Diego and Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.
Peter RossingSteno Diabetes Center Copenhagen, Herlev, and University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1531-4294
Richard John Mark CowardBristol Renal, University of Bristol, Bristol, UK.ORCID 0000-0001-6183-2546
Faiez ZannadInserm, Université de Lorraine, Centre d'Investigations Cliniques, Plurithématique 14-33, and Inserm U1116, CHRU Nancy, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France.ORCID 0000-0001-7456-1570
Hiddo J L HeerspinkDepartment of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0002-3126-3730

Funding

Bayer AG
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Extracellular matrix remodellingFibrosisFinerenoneMRANeuropeptide YProteomics

Identifiers

PMID40415577
PMCPMC12414561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.