Evidence map›Paper›PMID 40415424›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2025

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Peipei Tang, Yong Tan, Yanyun Yin, Xiaowei Nie, Jingyu Huang, Wenting Zuo, Yuling Li

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peipei TangAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Yong TanAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Yanyun YinAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Xiaowei NieAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Jingyu HuangAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Wenting ZuoAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Yuling LiAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the efficacy and safety of

methodsWe used bioinformatics analyses and network pharmacology to identify the main active ingredients in TZZY recipe and their core targets, which were verified by Western blotting. We tested the efficacy and safety of the recipe in 60 POI patients, who were randomized into control group (

resultsThe core active ingredients of TZZY recipe included kaempferol, β-sitosterol, luteolin, and quercetin. The core targets included

conclusionsThe therapeutic mechanism of TZZY recipe for POI involves multiple active ingredients, multiple therapeutic targets and multiple pathways, and activating the PI3K /Akt pathway is one of its main mechanisms of action, to improve ovarian reserve function, alleviate clinical symptoms, and enhance clinical efficacy in POI patients.

Indexed as

Drugs, Chinese HerbalPrimary Ovarian InsufficiencyAnimalsFemaleHumansKaempferolsMolecular Docking SimulationRatsSignal TransductionSitosterolsDrugs, Chinese Herbalgamma-sitosterolkaempferolKaempferolsSitosterolsclinical observationExperimental verificationNetwork pharmacologyPremature ovarian insufficiencyTiaozhou Ziyin recipe

Identifiers

PMID40415424
PMCPMC12104729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.