Evidence map›Paper›PMID 40415411›Full record

ArticleMagnetic resonance in medicine2025

MRI-based quantification of whole-organ renal metabolic rate of oxygen during free-breathing.

Nada Kamona, Michael C Langham, Rajiv S Deshpande, Brian-Tinh D Vu, Mahdie Hosseini, Jeffrey Dennison, Kathryn M Jaroszynski, Felix W Wehrli

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nada KamonaDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-4382-876X
Michael C LanghamDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rajiv S DeshpandeDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-1232-0875
Brian-Tinh D VuDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Mahdie HosseiniDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jeffrey DennisonDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kathryn M JaroszynskiDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Felix W WehrliDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-3430-1840

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Training Program in Musculoskeletal ResearchT32AR007132 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Robert L Mauck, LOUIS J SOSLOWSKY · 1986 to 2026
$4.9M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
MRI-Based Renal Oximetry in Early Diabetic Kidney DiseaseR21DK132556 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2023 to 2024
$439k
NCATS NIH HHS UL1 TR001878NCATS NIH HHS UL1TR001878NIAMS NIH HHS T32 AR007132NIBIB NIH HHS T32 EB020087NIDDK NIH HHS R21 DK132556
6 · The paper itself

Abstract

purposeRenal metabolic rate of oxygen (rMRO

methodsFree-breathing (FB) K-MOTIVE sequence (kidney metabolism of oxygen via T

resultsRenal venous blood was highly oxygenated (SvO

conclusionFB K-MOTIVE is a feasible approach to estimate rMRO

Indexed as

KidneyMagnetic Resonance ImagingOxygenAdultBreath HoldingFemaleHumansImage Processing, Computer-AssistedMaleRenal CirculationRespirationYoung AdultOxygenkidneymetabolismMRIoxygenation

Identifiers

PMID40415411
PMCPMC12309874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.