Evidence map›Paper›PMID 40415338›Full record

ReviewGut microbes2025

New insights in amino sugar metabolism by the gut microbiome.

Wenqiang Shen, Jan Freark de Boer, Folkert Kuipers, Jingyuan Fu

Abstract readReview
In one paragraph

Review in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Discovery of a secretedGut microbes · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Environmental and Maternal Imprints on Infant Gut Metabolic Programming.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenqiang ShenDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Jan Freark de BoerDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0001-6759-3291
Folkert KuipersDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0003-2518-737X
Jingyuan FuDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0001-5578-1236

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microorganisms inhabiting the intestinal tract play key roles in host's health and disease. A properly functioning gut microbiome requires the availability of adequate carbon, nitrogen and energy sources. One of the main sources of energy for intestinal bacteria are glycans, of which amino sugars are important components. Amino sugars are a class of carbohydrates in which one or more hydroxyl groups are substituted with amino groups. However, bacterial utilization of amino sugars and their impact on the gut microbiome and host health have not been thoroughly assessed. In this review, we summarize the latest discoveries about amino sugar metabolism by gut microbes, paying particular attention to the metabolism of N-acetyl-galactosamine (GalNAc), one of the most abundant amino sugars in the intestine, and its potential implications for microbial functionality and host health.

Indexed as

Amino SugarsBacteriaGastrointestinal MicrobiomeAcetylgalactosamineAnimalsGastrointestinal TractHumansAcetylgalactosamineAmino Sugarsamino sugar metabolismGalNAc utilization pathwayGut microbiomehost health

Identifiers

PMID40415338
PMCPMC12118421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.