ArticleRenal failure2025
Association between the serum uric acid-to-creatinine ratio and cardiovascular mortality in maintenance hemodialysis patients.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- A digital marker for stratifying cardiovascular metabolic comorbidities among the middle-aged and elderly adults.PLOS digital health · 2026Article
- Prognostic value of neutrophil percentage-to-albumin, uric acid-to-creatinine, and CRP-to-albumin ratios for mortality in patients on maintenance hemodialysis.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUric acid is a risk factor for death in hemodialysis patients, but its exact role is still unclear. The serum uric acid-to-serum creatinine (SUA/SCr) ratio is a new indicator. This study aimed to clarify the relationship between this indicator and cardiovascular death in maintenance hemodialysis patients.
methodsKaplan-Meier analysis was used to compare all-cause and cardiovascular mortality. Restricted cubic splines were used to plot the relationships between SUA/SCr and all-cause and cardiovascular mortality. Multivariable Cox regression was used to analyze the relationships between SUA/SCr and the risk of all-cause death or cardiovascular death. The C statistic was calculated to test the model discrimination performance. The net reclassification index was calculated to demonstrate the prediction accuracy of SUA and SUA/SCr.
resultsKaplan-Meier analysis showed that all-cause and cardiovascular mortality were significantly higher in the highest SUA/SCr quartile (
conclusionsIn maintenance hemodialysis patients patients, higher levels of SUA/SCr are associated with a greater risk of cardiovascular mortality.
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