Evidence map›Paper›PMID 40415040›Full record

ArticleWorld journal of microbiology & biotechnology2025

Rhamnolipids production in semi-submerged static-cultivation using agar cubes as solid substrate.

Mayara de Alencar Almeida, Karen Stefany Conceição, Juliana Perez Marques Teixeira, Nicole Caldas Pan, Luis Paulo Silveira Alves, Gerson Nakazato, Lucélia Donatti, Emanuel M Souza, Doumit Camilios-Neto, Josiane A Vignoli

Abstract read
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In one paragraph

Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mayara de Alencar AlmeidaDepartamento de Bioquímica e Biotecnologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Karen Stefany ConceiçãoDepartamento de Bioquímica e Biotecnologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Juliana Perez Marques TeixeiraDepartamento de Bioquímica e Biotecnologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Nicole Caldas PanDepartamento de Bioquímica e Biotecnologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Luis Paulo Silveira AlvesDepartamento de Bioquímica e Biotecnologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Gerson NakazatoDepartamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Lucélia DonattiDepartamento de Biologia Celular, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Emanuel M SouzaDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Doumit Camilios-NetoDepartamento de Bioquímica e Biotecnologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Josiane A VignoliDepartamento de Bioquímica e Biotecnologia, Universidade Estadual de Londrina, Londrina, PR, Brazil. javignoli@uel.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico senior Researcher fellowshipConselho Nacional de Desenvolvimento Científico e Tecnológico Universal 14/2014-45824/2014-2).Fundação Araucária Fixação de Jovens Doutores: CP 19/2022
6 · The paper itself

Abstract

Surfactants are amphiphilic molecules with a worldwide billionaire market. Although chemical surfactants are the most available and commonly used, the microbiologically produced congeners have attracted attention due to their low toxicity, biodegradability, and high ecological acceptability. Among microbial surfactants rhamnolipids stand out, with high yields of production, excellent surface-active properties and great potential market. However, the application of these compounds is still limited mostly because of excessive production costs. This study presents a cost-effective process for rhamnolipids production by semi-submerged static-cultivation using agar cubes as substrate. A concentration of 50 g/L of rhamnolipids was reached in semi-submerged static-cultivation using agar cubes containing corn bran and soybean oil. Through this static process, besides avoiding foam, gradual release of nutrients provides a large increase in P. aeruginosa growth and consequently on rhamnolipids production.

Indexed as

AgarCulture MediaGlycolipidsPseudomonas aeruginosaSoybean OilSurface-Active AgentsZea maysAgarCulture MediaGlycolipidsrhamnolipidSoybean OilSurface-Active Agents

Identifiers

PMID40415040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.