ArticleScientific reports2025
SGO enhanced random forest and extreme gradient boosting framework for heart disease prediction.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- HED-ID: an edge-deployable and explainable intrusion detection system optimized via metaheuristic learning.Scientific reports · 2026Article
- Leveraging Clinical Data for Early Heart Disease Prediction: A Machine Learning Approach With Interpretability Analysis.Biomedical engineering and computational biology · 2026Article
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3 authors.
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Abstract
Cardiovascular disease (CVD) remains a leading global health concern, accounting for approximately 31.5% of deaths worldwide. According to the World Health Organization (WHO), over 20.5 million people succumb to CVD each year-a figure projected to rise to 24.2 million by 2030. Early diagnosis is critical and can be facilitated by monitoring key risk factors such as cholesterol levels, blood pressure, diabetes, and obesity. This study proposes a heart disease prediction (HDP) model employing Random Forest (RF) and eXtreme Gradient Boosting (XGB) classifiers. Both models are further optimized through hyperparameter tuning using the Social Group Optimization (SGO) algorithm. The model was developed and validated using the Cleveland and Statlog datasets from the UCI repository. Pre-optimization results for RF yielded an accuracy (Acc.) of 84% and a ROC-AUC score of 92.03% on the Cleveland dataset, and 88.09% Acc. with a ROC-AUC of 97.50% on Statlog. The XGB classifier achieved 81.97% Acc. and a ROC-AUC of 90.73% on Cleveland, and 92.86% Acc. with a ROC-AUC of 96.14% on Statlog. After SGO-based optimization, RF improved to 95.08% Acc. and 95.26% ROC-AUC on Cleveland, and 95.24% Acc. with 98.18% ROC-AUC on Statlog. Similarly, the optimized XGB classifier reached 93.44% Acc. and 95.24% ROC-AUC on Cleveland, and 97.62% Acc. with 97.50% ROC-AUC on Statlog. These results highlight the effectiveness of SGO in enhancing ML performance for medical prediction problems. However, the study has certain limitations. The evaluation was conducted solely on two benchmark datasets, which may not fully reflect the diversity and complexity of real-world clinical populations. Furthermore, external validation using independent or real-time clinical data was not performed, which may limit the generalizability of the results. The computational cost associated with SGO optimization was also not assessed. Future research should focus on validating the model across broader datasets, assessing real-world applicability, and analyzing computational efficiency to ensure scalability and clinical adoption.
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