Observational studyEuropean journal of medical research2025
Symptom characteristics in patients undergoing acute type A aortic dissection surgery post-discharge phase: a prospective observational study.
Observational study in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesIn recent years, most studies on symptom characteristics in patients undergoing cardiac surgery have focused on the preoperative and postoperative phases. Relatively little knowledge is available related to the post-discharge phase. In this context, this paper aimed to analyze the symptoms and needs of patients with acute type A aortic dissection (AAAD) during the post-discharge phase.
methodsWe recruited and studied patients who underwent acute type A aortic dissection surgery at Fujian Heart Medical Center from June 2022 to August 2023. At 3 months following the surgery, these subjects were investigated using the general information questionnaire and relevant symptom assessment scales, including the Mini-Mental State Examination Scale (MMSE), Athens Insomnia Scale (AIS), Hospital Anxiety and Depression Scale (HADS), and Fatigue Severity Scale (FSS). Meanwhile, grip strength and average step per day were measured for the exercise endurance assessment. A latent class analysis (LCA) based on the symptoms was performed, and differences in demographic and disease characteristics among different subgroups of patients were identified and compared using multivariate logistic regression.
resultsA total of 228 patients were enrolled and categorized into three latent classes: fatigue-sleep disturbance (44.3%), anxiety-locomotion decline (16.9%), and high symptom groups (38.8%). Results showed that patients with cardiopulmonary bypass time > 200 min, higher BMI, or decreased grip strength were more likely to be classified as the high symptom group and those were unemployment status have a higher possibility of being defined as the anxiety-locomotion decline group.
conclusionsThe symptom characteristics in patients with AAAD during the postoperative rehabilitation phrase exhibit heterogeneity. It is suggested that Clinical healthcare personnel improve the identification of symptoms in high-risk patients, particularly patients cardiopulmonary bypass time > 200 min, overweight or obese, unemployed status or decreased grip strength, relevant nursing interventions should be carried out to prevent the occurrence of surgical stress and complications in patients with AAAD early to improve the quality of life of patients.
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