Evidence map›Paper›PMID 40414871›Full record

ArticleJournal of orthopaedic surgery and research2025

Proximal femur replacement in oncologic lesion: hemiarthroplasty vs total hip arthroplasty-a multicentric retrospective study.

Matteo Salvini, Giuseppe Malerba, Cesare Meschini, Alessandro El Motassime, Edoardo Venturini, Domenico Andrea Campanacci, Francesco Muratori, Simone Checcucci, Roberto Scanferla, Raffaele Vitiello and 1 more

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matteo SalviniOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy.
Giuseppe MalerbaDepartment of Orthopedics and Geriatric Sciences, Catholic University of the Sacred Heart, Largo Francesco Vito, 8, Rome, 00168, Italy.
Cesare MeschiniDepartment of Orthopedics and Geriatric Sciences, Catholic University of the Sacred Heart, Largo Francesco Vito, 8, Rome, 00168, Italy. cesare.meschini@gmail.com.ORCID http://orcid.org/0000-0003-2470-1189
Alessandro El MotassimeDepartment of Orthopedics and Geriatric Sciences, Catholic University of the Sacred Heart, Largo Francesco Vito, 8, Rome, 00168, Italy.
Edoardo VenturiniDepartment of Orthopedics and Geriatric Sciences, Catholic University of the Sacred Heart, Largo Francesco Vito, 8, Rome, 00168, Italy.
Domenico Andrea CampanacciDepartment of Orthopaedic Oncology and Reconstructive Surgery, Careggi University Hospital, Florence, Italy.
Francesco MuratoriDepartment of Orthopaedic Oncology and Reconstructive Surgery, Careggi University Hospital, Florence, Italy.
Simone CheccucciDepartment of Orthopaedic Oncology and Reconstructive Surgery, Careggi University Hospital, Florence, Italy.
Roberto ScanferlaDepartment of Orthopaedic Oncology and Reconstructive Surgery, Careggi University Hospital, Florence, Italy.
Raffaele VitielloDepartment of Orthopedics and Geriatric Sciences, Catholic University of the Sacred Heart, Largo Francesco Vito, 8, Rome, 00168, Italy.
Giulio MaccauroDepartment of Orthopedics and Geriatric Sciences, Catholic University of the Sacred Heart, Largo Francesco Vito, 8, Rome, 00168, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to evaluate the outcomes and complications associated with proximal femur replacement (PFR) in patients undergoing treatment for primary bone tumors or metastatic lesions. This research specifically compared modular hemiarthroplasty (HA) and total hip arthroplasty (THA) to ascertain the optimal approach regarding functionality and postoperative complications. MATERIALS AND

methodsA retrospective multicenter review was conducted involving 85 patients who underwent prosthetic femoral reconstruction (PFR) between the years 2015 and 2022 at two specialized medical centers. The patients were classified into two groups: 69 individuals received HA (Group A), while 16 individuals underwent THA (Group B). Outcomes were appraised utilizing the Harris Hip Score (HHS) and the Musculoskeletal Tumor Society (MSTS) score at three months post-surgery. Furthermore, the study assessed the rates of complications.

resultsThe overall complication rate was significantly lower in HA, at 24.6%), compared to THA, at 56.3% (p = 0.03). Infection rates were substantially higher in THA, reaching 37%, as opposed to HA, which recorded a rate of 6% (p = 0.002). Although dislocation rates were elevated in THA at 25%, compared to HA at 13%, this difference did not attain statistical significance (p = 0.2). Functional outcomes revealed no significant discrepancies, with HHS and MSTS scores being comparable across both groups (HHS: HA 62 ± 25 versus THA 61 ± 16, p = 0.9; MSTS: HA 17 ± 9 versus THA 14 ± 6, p = 0.5). Logistic regression analysis identified THA as a significant risk factor for infection (odds ratio [OR] = 45.3, p = 0.008) and dislocation (OR = 6.4, p = 0.05).

conclusionsProximal femur replacement with modular hemiarthroplasty appears to provide a safer alternative to total hip arthroplasty, characterized by a lower incidence of complications and comparable functional outcomes.

Indexed as

Arthroplasty, Replacement, HipBone NeoplasmsFemurHemiarthroplastyAdultAgedAged, 80 and overFemaleHip ProsthesisHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeHemiarthroplastyMegaprosthesesOncologic lesionProximal femurTHA

Identifiers

PMID40414871
PMCPMC12105249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.