Evidence map›Paper›PMID 40414850›Full record

ArticleBMC ophthalmology2025

Comparing the effects of orthokeratology lenses and highly aspherical lenslets on axial length in myopic anisometropia.

Minfeng Chen, Xianling Yang, Xibo Yu, Huihui Lei, Xinjie Mao

Abstract readComparative Study
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Real-world Evaluation of the Effectiveness of Highly Aspherical Lenslets and Orthokeratology In Anisomyopic Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  2. The Changing Natural History of Anisometropia: A Scoping Review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minfeng ChenWenzhou medical university eye hospital, Wenzhou, 325000, Zhejiang, China.
Xianling YangWenzhou medical university eye hospital, Wenzhou, 325000, Zhejiang, China.
Xibo YuWenzhou medical university eye hospital, Wenzhou, 325000, Zhejiang, China.
Huihui LeiWenzhou medical university eye hospital, Wenzhou, 325000, Zhejiang, China.
Xinjie MaoWenzhou medical university eye hospital, Wenzhou, 325000, Zhejiang, China. mxj@mail.eye.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study compares the influences of orthokeratology (OK) lenses and highly aspherical lenslets (HAL) on axial length (AL) in myopic anisometropia.

methodsRetrospective analysis was performed on 225 individuals with myopic anisometropia who agreed to wear OK lenses, HAL or single-vision spectacles (SP). Subjects with bilateral myopic anisometropia (BMA) were divided into the following groups: SP-BMA, HAL-BMA and OK-BMA. Further, children with unilateral myopic anisometropia (UMA) were divided into the following groups: SP-UMA, UHAL-UMA (unilateral HAL), BHAL-UMA (bilateral HAL) and OK-UMA (unilateral OK lens). Analyzed the difference in the interocular AL elongation in different groups.

resultsFor children with BMA, the interocular difference change in the OK-BMA group (0.15 ± 0.19 mm) was greater than that in the SP-BMA (-0.01 ± 0.20 mm) and HAL-BMA (-0.03 ± 0.17 mm) groups, all P < 0.001. For children with UMA, in the non-myopic eyes, the difference in AL elongation in the BHAL-UMA group (0.10 ± 0.14 mm) was less than that in the SP-UMA (0.28 ± 0.22 mm), UHAL-UMA (0.40 ± 0.22 mm) and OK-UMA (0.47 ± 0.24 mm) groups, all P < 0.001. The interocular change in the UHAL-UMA group (0.29 ± 0.36 mm) and OK-UMA group (0.35 ± 0.25 mm) were all higher than that in the SP-UMA (-0.02 ± 0.23 mm) and BHAL-UMA (0.01 ± 0.18 mm) groups, all P < 0.01.

conclusionsOK lenses can effectively reduce the interocular AL difference for children with unilateral or bilateral myopic anisometropia. However, HAL only decreased the interocular AL difference for children with UMA when wearing unilateral HAL but it did slow down the AL elongation of the non-myopic eyes in children with UMA when wearing bilateral HAL.

Indexed as

AnisometropiaAxial Length, EyeContact LensesEyeglassesMyopiaOrthokeratologic ProceduresAdolescentChildFemaleHumansMaleRefraction, OcularRetrospective StudiesVisual AcuityAnisometropiaAxial lengthMyopia controlOrthokeratology

Identifiers

PMID40414850
PMCPMC12105321

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.