Evidence map›Paper›PMID 40414690›Full record

ArticleMedical physics2025

Reference datasets for commissioning of model-based dose calculation algorithms for electronic brachytherapy.

Iymad R Mansour, Christian Valdes-Cortez, David Santiago Ayala Alvarez, Francisco Berumen, Jean-Simon Côte, Gaël Ndoutoume-Paquet, Peter G F Watson, Jan Seuntjens, Facundo Ballester, Ernesto Mainegra-Hing and 3 more

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Iymad R MansourCarleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University, Ottawa, Canada.
Christian Valdes-CortezNuclear Medicine Department, Hospital Regional de Antofagasta, Antofagasta, Chile.
David Santiago Ayala AlvarezDepartment of Physics and Medical Physics Unit, McGill University, Montreal, Canada.
Francisco BerumenService de Physique Médicale et de Radioprotection, Centre Intégré de Cancérologie, CHU de Québec- Université Laval et Centre de recherche du CHU de Québec, Québec, Canada.
Jean-Simon CôteDepartment of Physics and Medical Physics Unit, McGill University, Montreal, Canada.
Gaël Ndoutoume-PaquetService de Physique Médicale et de Radioprotection, Centre Intégré de Cancérologie, CHU de Québec- Université Laval et Centre de recherche du CHU de Québec, Québec, Canada.
Peter G F WatsonDepartment of Physics and Medical Physics Unit, McGill University, Montreal, Canada.
Jan SeuntjensDepartment of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.
Facundo BallesterDepartamento de Física Atómica, Molecular y Nuclear, Universitat de Valencia (UV), Burjassot, Spain.
Ernesto Mainegra-HingMetrology Research Centre, National Research Council Canada, Ottawa, Canada.
Rowan M ThomsonCarleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University, Ottawa, Canada.
Luc BeaulieuService de Physique Médicale et de Radioprotection, Centre Intégré de Cancérologie, CHU de Québec- Université Laval et Centre de recherche du CHU de Québec, Québec, Canada.
Javier VijandeDepartamento de Física Atómica, Molecular y Nuclear, Universitat de Valencia (UV), Burjassot, Spain.

Funding

AEICIHR FDN-143257Conselleria de Educación, Universidades y Empleo (GVA) CIPROM/2021/64MCIN"ERDF A way of making Europe" by the "European Union NextGenerationEU/PRTR" PID2021-125096NB-I00Fonds de Recherche du Québec-Santé 292924JCyL SA091P24Natural Sciences and Engineering Research Council 546549-2020Natural Sciences and Engineering Research Council RGPIN2019-05038Natural Sciences and Engineering Research Council RGPIN-2019-06746Natural Sciences and Engineering Research Council RGPIN-2024-05355
6 · The paper itself

Abstract

purposeThis work provides the first two clinical test cases for commissioning electronic brachytherapy (eBT) model-based dose calculation algorithms (MBDCAs) for skin irradiation using surface applicators. ACQUISITION AND VALIDATION

methodsThe test cases utilize the INTRABEAM 30 mm surface applicator. Test Case I: water phantom is used to evaluate the algorithm's performance in a uniform medium consisting of a voxelized water cube surrounded by air. Test Case II: Surface eBT represents a heterogeneous medium with four distinct layers: skin tissue, adipose tissue, cortical bone, and soft tissue. Treatment plans for both cases were created and exported into the Radiance treatment planning system (TPS). Dose-to-medium calculations were then performed using this Monte Carlo (MC)-based TPS and compared with MC simulations conducted independently by three different groups using two codes: EGSnrc and PENELOPE. The results agreed within expected Type A and B statistical uncertainties. DATA FORMAT AND USAGE NOTES: The dataset is available online at https://doi.org/10.52519/00005. A proprietary file designed for use within Radiance containing CT images and the treatment plan for both test cases, the LINAC modeling, and the CT calibration are included, as well as reference MC and TPS dose data in RTdose format and all files required to run the MC simulations. POTENTIAL APPLICATIONS: This dataset serves as a valuable resource for commissioning eBT MBDCAs and lays the groundwork for developing clinical test cases for other eBT systems. It is also a helpful educational tool for exploring various eBT devices and their advantages and drawbacks. Furthermore, brachytherapy researchers seeking a benchmark for dosimetric calculations in the low-energy domain will find this dataset indispensable.

Indexed as

AlgorithmsBrachytherapyDatasets as TopicRadiation DosageRadiotherapy Planning, Computer-AssistedHumansMonte Carlo MethodPhantoms, ImagingRadiotherapy Dosageintraoperative radiation therapy (IORT)model based dose calculation algorithms (MBDCA)Monte Carlo (MC)

Identifiers

PMID40414690
PMCPMC12258003

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.