Evidence map›Paper›PMID 40414088›Full record

Trial reportSocial science & medicine (1982)2025

Social network intervention to improve blood pressure control after stroke: The TEAMS-BP randomized clinical trial.

Amar Dhand, Katherine Crum, Kaitlin E Hanken, Gauri Bhatkhande, Melinda Luo, Ian M Corbin, George Usmanov, Zachary Rothfeld-Wehrwein, Vrushali Dhongade, David Lin and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Social science & medicine (1982), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05258890 (TEAMS-BP), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05258890 naterminatednot on this map

TEAMS-BP (The Enhancement of Social Networks to Augment Management of Stroke-Blood Pressure): A Randomized Control Trial

TypeinterventionalSponsorBrigham and Women's HospitalRan2022 to 2024Enrolled64ConditionsStroke, Acute Ischemic, HypertensionArmsSocial Network Group Counseling, Individual Counseling
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amar DhandBrigham and Women's Hospital, Department of Neurology, 65 Landsdowne Street, Cambridge, MA, 02139, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA; Northeastern University, Network Science Institute, 177 Huntington Ave #1010, Boston, MA, 02115, USA. Electronic address: adhand@bwh.harvard.edu.
Katherine CrumBrigham and Women's Hospital, Center for Healthcare Delivery Sciences (C4HDS), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, 1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA.
Kaitlin E HankenBrigham and Women's Hospital, Center for Healthcare Delivery Sciences (C4HDS), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, 1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA.
Gauri BhatkhandeBrigham and Women's Hospital, Center for Healthcare Delivery Sciences (C4HDS), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, 1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA.
Melinda LuoBrigham and Women's Hospital, Department of Neurology, 65 Landsdowne Street, Cambridge, MA, 02139, USA.
Ian M CorbinBrigham and Women's Hospital, Department of Neurology, 65 Landsdowne Street, Cambridge, MA, 02139, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
George UsmanovBrigham and Women's Hospital, Department of Neurology, 65 Landsdowne Street, Cambridge, MA, 02139, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
Zachary Rothfeld-WehrweinBrigham and Women's Hospital, Department of Neurology, 65 Landsdowne Street, Cambridge, MA, 02139, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
Vrushali DhongadeBrigham and Women's Hospital, Department of Neurology, 65 Landsdowne Street, Cambridge, MA, 02139, USA.
David LinHarvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA; Massachusetts General Hospital, Department of Neurology, Division of Neurocritical Care and Stroke Service, Center for Neurotechnology and Neurorecovery, Suite #310, 101 Merrimac St., Boston, MA, 02114, USA.
Chloe SlocumHarvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA; Spaulding Rehabilitation Hospital, 300 1st Ave, Charlestown, MA, 02129, USA.
Nancy HaffHarvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA; Brigham and Women's Hospital, Center for Healthcare Delivery Sciences (C4HDS), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, 1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA.
Niteesh K ChoudhryHarvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA; Brigham and Women's Hospital, Center for Healthcare Delivery Sciences (C4HDS), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, 1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA.

Funding

The Roybal Center for TherapeuticOptimization using BehavioralScienceP30AG064199 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Julie Christine Lauffenburger · 2019 to 2026
$8.3M
NIA NIH HHS P30 AG064199
6 · The paper itself

Abstract

Social connections play an important role in predicting health outcomes after a stroke. In the context of clinical medicine, a social network theory proposes that each patient is embedded in a personal social network of interpersonal connections that provide social support, information, and behavioral cues. However, the effectiveness of activating and harnessing supportive personal social networks remains uncertain, particularly within healthcare situations where individualism prevails. As an initial step towards developing interventions for healthier social networks in clinical practice, we conducted a randomized controlled trial in stroke survivors. This trial compared a network intervention versus individual counseling for 3 months with the aim of lowering blood pressure after stroke. Over 2 years, we recruited 45 stroke survivors, with 24 assigned to the network intervention and 21 to the individual counseling group. Results indicated no significant difference in the primary outcome of absolute systolic blood pressure difference over 3 months between the two groups. However, subgroup analyses revealed that patients within small and close-knit networks, known as high constraint networks, who received the network intervention had a significantly larger reduction in blood pressure than patients within large and open, low constraint, networks. The study's findings are preliminary due to dropout rates in both arms, and variable engagement of network members in the intervention arm. Nevertheless, our results suggest the potential of leveraging social networks to enhance health outcomes in specific subgroups of stroke survivors, highlighting avenues for further research and intervention development. Clinical Trial Unique Identifier: NCT05258890.

Indexed as

HypertensionSocial SupportStrokeAgedBlood PressureCounselingFemaleHumansMaleMiddle AgedBlood pressureRandomized controlled trialSocial networkingSocial supportStroke

Identifiers

PMID40414088
PMCPMC12230982

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.