ArticleAssessment2026
Cognitive Performance in Parkinson's Spectrum Disorders: a comparative study of patients with Parkinson's Disease, Parkinson's Disease Dementia, Dementia With Lewy Bodies, Progressive Supranuclear Palsy, and Corticobasal Syndrome.
Article in Assessment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Plasma Alzheimer Biomarkers and Diagnostic Decision-Making in Memory Clinics.JAMA network open · 2026Article
- Revealing cerebrospinal fluid biomarkers in Parkinson's disease dementia based on iTRAQ proteomics research.Frontiers in neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Parkinson's spectrum encompasses Parkinson's disease (PD), PD dementia (PDD), dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP), and corticobasal syndrome (CBS). Clinical diagnosis mainly relies on progression over time and neuroimaging, biomarkers, and neurological observations, aided by neuropsychological assessment. Neuropsychological profiles and differences within the Parkinson's spectrum have been understudied. This retrospective study analyzed mean performance and proportions of impairment of neuropsychological assessments of 212 patients in the Parkinson's spectrum at an academic outpatient memory clinic. Patients with PD scored significantly higher than the other patient groups on most tests. The other patient groups showed limited significant differences from one another. The letter fluency test was most effective in distinguishing PD from the other disorders. The auditory verbal learning test was suitable to distinguish PDD and DLB from the other disorders. Results indicate considerable overlap in cognitive profiles across Parkinson's spectrum disorders, suggesting neuropsychological assessment is valuable for assessing cognitive function, guiding post-diagnostic support, and monitoring progression, rather than differential diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.