Evidence map›Paper›PMID 40413440›Full record

ArticleBMC pediatrics2025

Factors associated with severe bacterial infection in infants between 91- and 120-days old admitted to the pediatric emergency department.

Bei-Cyuan Guo, Han-Ping Wu, Yin-Ting Chen, Yu-Jun Chang, Chun-Yu Chen, Wen-Ya Lin, Chung-Hao Su

Abstract read
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Bei-Cyuan Guo *Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Han-Ping Wu *College of Medicine, Chang Gung University, Taoyuan, Taiwan. arthur1226@gmail.com.
Yin-Ting ChenDivision of Neonatology, Department of Pediatrics, Children Hospital, China Medical University, Taichung, Taiwan.
Yu-Jun ChangLaboratory of Epidemiology and Biostastics, Changhua Christian Hospital, Changhua, Taiwan.
Chun-Yu ChenDepartment of Emergency Medicine, Tungs' Taichung Metro Harbor Hospital, Taichung, Taiwan.
Wen-Ya LinDepartment of Pediatric Emergency Medicine, Department of Pediatrics, Taichung Veteran General Hospital, Taichung, Taiwan.
Chung-Hao SuDivision of Neonatology, Department of Pediatrics, Chiayi Chang-Gung Memorial Hospital, Chiayi County, No. 6, W. Sec., Jiapu Rd, Puzi City, Taiwan. b9302049@cgmh.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiagnosing severe bacterial infections (SBI) can be challenging, especially in infants. This study sought to identify clinical factors that could aid in predicting SBI in infants aged 91-120 days.

methodsThis retrospective cohort study investigated febrile infants aged 91-120 days admitted to the pediatric emergency department (PED). This study assessed the significant predictors of clinical and laboratory data for identifying SBI in young infants.

resultsThis study analyzed 264 febrile infants aged 91-120 days admitted to the PED. The significant factors for infants with SBI included sex, admission weight, body temperature(BT), white blood cell (WBC) count, neutrophil percentage, and C-reactive protein (CRP) level (all P < 0.05). Logistic regression analysis showed that male sex, higher BT, WBC count, and CRP levels were predictors of SBI. ROC analysis identified the useful cutoff values for predicting SBI as a BT of 39.3 °C, WBC counts of 15,500/µL, and a CRP concentration of 14.4 mg/L.

conclusionsIncreased BT, elevated WBC and neutrophil counts, as well as higher CRP levels, may act as predictors of SBI in infants aged 91-120 days admitted to the PED.

Indexed as

Bacterial InfectionsEmergency Service, HospitalBody TemperatureC-Reactive ProteinFemaleFeverHospitalizationHumansInfantLeukocyte CountLogistic ModelsMaleNeutrophilsRetrospective StudiesRisk FactorsROC CurveC-Reactive Protein91-120 DaysEmergency departmentFeverInfantSevere Bacterial Infection

Identifiers

PMID40413440
PMCPMC12102981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.