Trial reportBMC oral health2025
The use of free buccal pad fat graft as a viable therapeutic modality in localized gingival recession: a randomized controlled clinical trial.
Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Oral stem cells in combination with hydrogels as biomimetic bioactive platforms for periodontal tissue engineering.Frontiers in oral health · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe buccal fat pad (BFP) is a unique, encapsulated fatty tissue that retains its volume and structure over time and contains undifferentiated mesenchymal cells. It has been used in various surgical techniques, such as closing oroantral and oronasal communications and repairing defects due to trauma or malignancy. A few years ago, the buccal fat pad was utilized as a pedicle or free soft tissue graft to treat gingival recessions. Therefore, this randomized clinical trial (RCT) was conducted to assess the effectiveness of the free buccal fat pad graft (FBPFG) compared to the de-epithelialized free gingival graft (DFGG) in conjunction with coronally advanced flap (CAF) in localized gingival recession treatment. MATERIALS AND
methodsThis RCT included 39 participants, with 20 patients receiving a coronally advanced flap (CAF) with FBPFG (Group I) and 19 patients treated with CAF and DFGG (Group II). Clinical parameters such as probing depth (PD), clinical attachment level (CAL), recession depth (RD), width of keratinized gingiva (WKG), and gingival thickness (GT) were assessed after 3- and 6 months of surgical intervention.
resultsAfter 3- and 6-month follow-ups, statistically significant changes were noted between the groups in all clinical parameters. At 1st and 2nd days of surgical intervention, there was a statistically significant decrease in the values of the visual analogue scale (VAS) in group I compared to group II. Regarding dentinal hypersensitivity, there were statistically significant variations of 3- and 6-month parameters compared to baseline in the two groups. However, there were no differences between the two after the therapy.
conclusionIt was proven that DFGG produces significantly better outcomes than FBPFG in treating localized gingival recession. However, FBPFG might serve as a viable alternative for mild to moderate gingival recession cases, where only a limited reduction in recession depth and modest increase in gingival thickness and width of keratinized tissues are required, with the benefit of lower donor site morbidity.
trial registrationThis randomized controlled clinical trial was registered on the Pan African Clinical Trials Registry and approved on 22/06/2023 (Trial no: PACTR202307891237031).
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