Evidence map›Paper›PMID 40413307›Full record

ArticleScientific reports2025

Phylogenetic analysis of the enigmatic Kalash population in Pakistan.

Imran Shahid, Faqeeha Javed, Abida Shehzadi, Jaweria Munsif, Ahmad Ali Shahid, Muhammad Shafique

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Imran ShahidForensic DNA Typing Laboratory, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Faqeeha JavedForensic DNA Typing Laboratory, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Abida ShehzadiForensic DNA Typing Laboratory, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Jaweria MunsifForensic DNA Typing Laboratory, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Ahmad Ali ShahidForensic DNA Typing Laboratory, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Muhammad ShafiqueForensic DNA Typing Laboratory, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan. shafique@cemb.edu.pk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetic origin of the Kalash, an isolated community in northern Pakistan, have long been a subject of debate. This study aimed at investigating the genetic diversity and ancestral composition of Kalash people using an advanced set of genetic data including 22 autosomal and 23 Y chromosomal STRs. We elucidated their historical movements and potential connections to ancient populations by investigating their distinct alleles and comparing them with other regional and global populations to catalog their phylogenetic associations. Based on autosomal STR data, Kalash population demonstrated its unique genetic structure from Asians, Europeans and Africans however, Y-STR haplogroups presented its ancient associations with Eurasian-Indo Iranian metapopulation. We found that the Kalash population is an example of cultural diversity retention following a significant genetic drift, with some affinity to West Eurasian populations and a lack of population admixture with Indian and Indo-European Pakistani populations. This study underscores the importance of preserving the genetic and cultural heritage of this isolated community. Future research should be based on longitudinal studies to investigate their migration patterns and interplay of genetic and environmental factors influencing their health and adaptability. Moreover, comparative studies with other isolated populations worldwide should be instigated.

Indexed as

EthnicityGenetics, PopulationPhylogenyChromosomes, Human, YGenetic VariationHaplotypesHumansMaleMicrosatellite RepeatsPakistanAdmixtureGenetic diversityKalashPhylogenetic analysisSTRsStructure analysis

Identifiers

PMID40413307
PMCPMC12103519

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