Evidence map›Paper›PMID 40413229›Full record

ArticleScientific reports2025

Red blood cell distribution width to albumin ratio and urinary incontinence subtypes in NHANES 2007-2018.

Tingxuan Lv, Yonghui Liu, Jinhui Yang, Mingyue Wang, Cheng Bo

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Tingxuan LvDepartment of Urology, School of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Yonghui LiuDepartment of Urology, School of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Jinhui YangDepartment of Urology, Shengli Oilfield Central Hospital, Dongying, China. yjhmx1987@126.com.
Mingyue Wang *Department of Urology, Shengli Oilfield Central Hospital, Dongying, China. myzxyy@outlook.com.
Cheng Bo *Department of Urology, Shengli Oilfield Central Hospital, Dongying, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate the relationships among a novel inflammatory biomarker, the red blood cell distribution width-to-albumin ratio (RAR), and three different types of urinary incontinence (UI) while evaluating the potential clinical significance of the biomarker. The National Health and Nutrition Examination Survey (NHANES)-which spanned 2007-2018-was used in this investigation. The relationship between the RAR and the prevalence of UI was assessed by logistic regression modeling, restricted cubic spline curve (RCS) analysis, and subgroup analysis. Fully adjusted models revealed a significant positive correlation between the RAR and all three types of UI (SUI: OR 1.23, 95% CI 1.12-1.35; UUI: OR 1.43, 95% CI 1.31-1.56; MUI: OR 1.44, 95% CI 1.27-1.62; all p < 0.05). Dividing the RAR into quartiles illustrated that an increased RAR was positively correlated with UI compared with a decreased RAR (SUI: OR 1.40, 95% CI 1.22-1.60; UUI: OR 1.85, 95% CI 1.60-2.14; MUI: OR 1.81, 95% CI 1.47-2.21; all p < 0.05). A nonlinear, inverted "U"-shaped relationship between the RAR and UI was demonstrated using restricted cubic spline analysis, suggesting that the RAR impacted UI only until reaching a threshold. Additionally, subgroup analysis revealed a stronger link between the RAR and SUI in women than in men (p < 0.05). An increased RAR was correlated with a heightened risk of UI, and RAR was more strongly associated with stress urinary incontinence (SUI) in women than in men. Systematic epidemiologic evidence suggests that the novel inflammatory marker RAR is associated with UI, but more research is needed to determine causality.

Indexed as

Erythrocyte IndicesErythrocytesUrinary IncontinenceAdultAgedBiomarkersFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceBiomarkersInflammationNHANESRARUI

Identifiers

PMID40413229
PMCPMC12103605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.