Evidence map›Paper›PMID 40412818›Full record

Trial reportBMJ open gastroenterology2025

Assessing water-assisted colonoscopy in beginner endoscopists: a randomised controlled trial.

Nuttida Manoros, Nithi Thinrungroj, Wasuwit Wanchaitanawong, Kanokwan Pinyopornpanish, Phuripong Kijdamrongthum, Apinya Leerapun, Taned Chitapanarux, Satawat Thongsawat, Ong-Ard Praisontarangkul

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMJ open gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nuttida ManorosDivision of Gastroenterology, Department of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Nithi ThinrungrojDivision of Gastroenterology, Department of Medicine, Chiang Mai University, Chiang Mai, Thailand nithi.th@cmu.ac.th.ORCID http://orcid.org/0000-0001-7355-2680
Wasuwit WanchaitanawongDivision of Gastroenterology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.ORCID http://orcid.org/0000-0001-7221-4196
Kanokwan PinyopornpanishDivision of Gastroenterology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.
Phuripong KijdamrongthumDivision of Gastroenterology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.
Apinya LeerapunDivision of Gastroenterology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.
Taned ChitapanaruxDivision of Gastroenterology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.
Satawat ThongsawatDivision of Gastroenterology, Department of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Ong-Ard PraisontarangkulDivision of Gastroenterology, Department of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare water-assisted colonoscopy (WAC) using the water immersion technique with conventional carbon dioxide insufflation colonoscopy (CC) in novice endoscopists, focusing on procedure time, safety and learning curves.

methodsWe conducted a prospective, randomised (1:1), single-centre trial at Chiang Mai University Hospital, Thailand. Six gastroenterology fellows with <150 prior colonoscopies received standardised training before performing elective screening colonoscopies using either WAC or CC techniques. Patients were randomly assigned to WAC or CC groups. The primary outcome was caecal intubation time (CIT). Secondary outcomes included technical failure, procedural difficulty, patient discomfort, complications, withdrawal time and adenoma detection rate (ADR).

resultsOf 250 randomised patients, 230 completed the protocol (WAC, n=113; CC, n=117). Mean CIT was comparable between groups (10.6±4.2 min vs 9.8±3.9 min; p=0.35). Technical failure occurred in 6.2% of WAC and 5.1% of CC procedures, with no significant differences in procedural difficulty ratings, analgesic requirements or patient discomfort scores. ADR was similar between arms (40.7% vs 33.3%; p=0.25). Learning curves demonstrated parallel, progressive reductions in CIT among fellows in both groups.

conclusionWAC is a safe and effective alternative to CC for novice endoscopists, with similar procedure times, learning curves and safety profiles. These findings support the inclusion of WAC in gastroenterology training programmes. TRIAL REGISTRATION NUMBER: TCTR20230324001.

Indexed as

ColonoscopyWaterAdenomaAdultAgedCarbon DioxideClinical CompetenceFemaleGastroenterologyHumansImmersionInsufflationLearning CurveMaleMiddle AgedProspective StudiesCarbon DioxideWaterCOLONOSCOPYCOLORECTAL CANCER SCREENINGDIAGNOSTIC AND THERAPEUTIC ENDOSCOPYENDOSCOPYGASTROINTESINAL ENDOSCOPY

Identifiers

PMID40412818
PMCPMC12104895

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.