ArticleDrug and alcohol dependence2025
Prevalence and correlates of self-reported new psychoactive substance use among adults in 20 US cities: Results from National Drug Early Warning System surveillance.
Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Assessment of drug harm by final-year medical students and ChatGPT - a comparative analysis.Substance abuse treatment, prevention, and policy · 2026Article
- Surveillance of emerging drug trends: utilizing the National Drug Early Warning System.Current opinion in psychiatry · 2026Review
- Key Considerations in the Design of a Sentinel Network for Drug Use: Qualitative Findings.Research square · 2025Article
- The Epidemiology of Recreational Use and Availability of DOC and DOI in the United States.Journal of psychoactive drugs · 2025Article
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3 authors.
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Abstract
backgroundAs new psychoactive substances (NPS) continue to emerge both in the US and globally, it is important to investigate characteristics of persons who use these substances.
methodsData on self-reported NPS use come from the National Drug Early Warning Rapid Street Reporting study, which uses a venue-intercept design to assess drug use and associated adverse effects among adults (≥18 years) in a given US city over a weekend period. Between January 2022 and November 2023, 6039 individuals were surveyed in person in 20 unique cities regarding prevalence and correlates of past 12-month NPS and other drug use.
resultsIn the overall sample, 259 (4.3 %) individuals reported any past 12-month NPS use. Synthetic cannabinoids (n = 150, 2.5 %), novel opioids (n = 34, 0.6 %), and synthetic cathinones (n = 33, 0.6 %) were the most frequently reported NPS classes used. Those also reporting past 12-month common stimulant use (aOR=2.39, 95 % CI:1.68-3.39) and a higher number of common drugs used in the past 12 months (aOR=1.28, 95% CI:1.18-1.40) had higher odds of reporting any NPS use; those with a college education were found to have lower odds of reporting NPS use (aOR=0.46, 95% CI:0.28-0.78).
conclusionsWhile the self-reported use of individual classes of NPS was low relative to other drugs in this large, multi-city sample, NPS use was most common among those reporting polysubstance use. Those who used synthetic cannabinoids appeared to represent a distinct subgroup. Given the continued public health concern posed by NPS, surveys which systematically ask about specific NPS are increasingly needed.
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