Evidence map›Paper›PMID 40411747›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA2025

Linguistic markers for identifying post-traumatic stress disorder and associated symptoms: a systematic literature review.

Robin Quillivic, Yann Auxéméry, Frédérique Gayraud, Jacques Dayan, Salma Mesmoudi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robin QuillivicCESSP UMR 8209, PSL-EPHE, Paris 75013, France.ORCID 0009-0009-9372-0173
Yann AuxéméryINSPIIRE, UMR 1319, Université de Lorraine, Metz 57000, France.
Frédérique GayraudLaboratoire dynamique du langage UMR 5596, Université Lyon II, Lyon 69000, France.
Jacques DayanNIMH U1077, Université de Caen Normandie, Caen 14118, France.
Salma MesmoudiCESSP UMR 8209, Université Paris1 Panthéon-Sorbonne, Paris 75001, France.

Funding

French General Secretariat for InvestmentNational Research AgencyProgramme d'investissement pour l'Avenir PIA ANR-10-EQPX-0021-01Region île-de-France
6 · The paper itself

Abstract

objectivesDiagnosing post-traumatic stress disorder (PTSD) remains a challenge due to symptom variability and comorbidities. Linguistic analysis offers an innovative approach to identify PTSD symptoms and severity. This systematic review aimed at identifying linguistic features associated with PTSD, assessing the quality and limitations of existing studies, summarizing the predictive performance of identified models, and describing the clinical utility of these models. MATERIALS: A comprehensive search was conducted across multiple databases, resulting in the identification of 593 articles. After screening and eligibility assessment, 58 studies were included.

methodsData extraction focused on study characteristics, methodology, and performance metrics. We assessed the risk of bias using the PROBAST and conducted both a narrative synthesis and a meta-analysis.

resultsLinguistic features such as pronoun use, emotional valence, cognitive processing words, narrative length, discourse disorganization, temporal orientation, specific lexical fields (death, anxiety, sensory-perception details), and disfluencies were commonly investigated. The meta-analysis revealed a pooled area under the curve of 0.81, indicating the high performance of classification models. However, significant publication bias and heterogeneity were noted. Only 8 studies were rated with a low risk of bias, highlighting common issues such as inadequate control groups, unvalidated linguistic tools, unvalidated diagnosis tools, and low rigor in statistical analysis. DISCUSSION AND

conclusionsLinguistic markers showed potential for enhancing PTSD diagnoses, but the contemporary research was limited by methodological inconsistencies and biases. Future research should focus on standardized tools, symptom-focused studies, and interdisciplinary collaboration to improve the robustness and clinical applicability of findings.

Indexed as

LinguisticsStress Disorders, Post-TraumaticHumansclinical decision support system (CDSS)linguisticnatural language processingPTSDsystematic review

Identifiers

PMID40411747
PMCPMC12277704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.