Evidence map›Paper›PMID 40411740›Full record

ArticleOphthalmology and therapy2025

Symptomology and Impact of Dry Eye Disease: A Patient and Physician Perspective.

Noel Cheong, Juliana Hiok-Lian Ang, Cansu Kaya, Ashish Kumar, Sean Shao Wei Lam, Louis Tong

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Noel CheongDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.ORCID http://orcid.org/0000-0001-7053-7303
Juliana Hiok-Lian AngPatient Author, Singapore, Singapore.
Cansu KayaDepartment of Ophthalmology, Mugla Sitki Kocman University School of Medicine, Kotekli, Mugla, Turkey.ORCID http://orcid.org/0000-0002-2230-3008
Ashish KumarSingHealth Health Services Research Centre, Singapore, 169856, Singapore.ORCID http://orcid.org/0000-0002-8280-1615
Sean Shao Wei LamSingHealth Health Services Research Centre, Singapore, 169856, Singapore.ORCID http://orcid.org/0000-0002-0898-5858
Louis TongSingapore National Eye Centre, 11, Third Hospital Avenue, Singapore, 168751, Singapore. louis.tong.h.t@singhealth.com.sg.ORCID http://orcid.org/0000-0002-3986-6552

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dry eye disease (DED) is a common ocular surface disease that results from tear instability, leading to visual disturbance, decreased work productivity, and reduced quality of life. Contributing factors to DED are multifactorial, ranging from air quality to Sjögren's syndrome (primary or secondary), and the associated comorbidities make management particularly challenging. Additionally, knowledge on the natural history of dry eye is lacking, and there is no consensus on the optimal treatment for various DED subtypes and their comorbidities. It is critical that information remains accurate and accessible to patients, caregivers, and physicians. Here, the experiences of a patient with DED are contextualized by an ophthalmologist with a review of the current available literature on DED to establish a groundwork for future research into DED. The patient experience suggests that a clear and accessible information source for patients and caregivers remains an overlooked aspect of holistic care in DED. Symptoms such as watery eyes and refractive changes are often not well understood by patients, and a systems-based approach suggests that patient care would benefit from multidisciplinary collaborations between ophthalmologists, general physicians, and other health professionals in managing this chronic condition. Further advancements in DED research and delivery of care will depend on increasing community engagement on DED diagnosis, comorbidities, and current evidence-based treatment protocols.

Indexed as

Dry eye diseaseInter-professional managementMeibomian gland dysfunctionPatient educationPatient perspectiveSjögren’s syndrome

Identifiers

PMID40411740
PMCPMC12167222

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.