Evidence map›Paper›PMID 40411690›Full record

ArticleDiscover oncology2025

Endoscopic thyroidectomy for central lymph node dissection-is there a difference in the number of lymph node dissections performed through different surgical approaches? A retrospective cohort study and pooled data research.

Zheng Wang, Han Yan, Jun Yu, Rui Sha, Zhao Cai Yin, Bin Chen, Ya Bing Wang, Chang Sheng Yu

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zheng Wang *Department of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China.
Han Yan *Department of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China.
Jun Yu *Department of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China.
Rui ShaDepartment of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China.
Zhao Cai YinDepartment of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China.
Bin ChenDepartment of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China. chenbin11234@163.com.
Ya Bing WangDepartment of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China. wangeb3@wnmc.edu.cn.
Chang Sheng YuDepartment of Thyroid and Breast Surgery, Yijishan Hospital, First Affiliated Hospital of Wannan Medical College, Zheshan West Rd No. 2, Wuhu, 241001, Anhui, China. yuchangsheng2022@126.com.

Funding

Anhui Provincial Health Commission An Wei Lai breast cancer Special Fund AHWJ2023BAb20032Anhui Provincial Health Commission Hengrui Innovative Drug Research Special Fund AHWJ2023BAc10053Foundation for High-level Talents of Provincial Public Medical and Health Institutions GCCRC2022018Integrated development of universities and enterprises-HengRui Research Foundation XQHR202415Integrated development of universities and enterprises-QiLu Research Foundation XQQL202409Key scientific research project of Anhui Provincial Department of Education 2024AH051951Research Foundation for Talents of Yijishan Hospital of Wannan Medical College YR202205Special Scientific Research Fund of Wu Jie-ping Medical Foundation 32067502024-21-102Teaching and Research Project of Anhui Provincial Department of Education 2023jyxm1220The teaching Quality and Teaching Reform Project of Wannan Medical College 2022jyxm60
6 · The paper itself

Abstract

backgroundEndoscopic thyroidectomies are commonly performed for thyroid cancer. Previous studies indicated that trans-areola approach is inferior in central lymph node dissection (CLND) due to clavicle protruding. The present study aimed to compare different surgical approaches of endoscopic thyroidectomies regarding surgical outcomes.

methodsRetrospective analysis of 153 patients underwent endoscopic thyroidectomies through oral and areola approaches from Nov. 2019 to Dec. 2022 in our institution, baseline information, surgical outcomes and postoperative complications were recorded and analyzed. For pooled data analysis, comprehensive searching was done to identify studies concerning comparison of endoscopic thyroidectomies. Basic information and surgical outcomes were extracted. RevMan 5.4 was used to analyze the pooled data. p < 0.05 was considered statistically different.

resultsA total of 153 patients were included with 75 in oral, 78 in areola. The operative time was longer in oral compared with other two groups. Number of lymph nodes, positive lymph nodes, hospital stay, postoperative drainage and complications were not different between the two groups. For the systematic review, five studies of oral and areola comparisons containing 568 patients was finally included in the meta-analysis. The operative time was slightly longer in oral group. Number of positive lymph nodes were slightly larger in areola. The blood loss, lymph nodes, hospital stay and transient hoarseness were not different between oral and areola.

conclusionsOral demanded more operative time than other approaches. Lymph nodes, positive lymph nodes and hospital stay were similar between different groups. Areola was comparable with oral in lymph nodes and positive lymph nodes.

Indexed as

Central lymph nodes dissectionEndoscopic thyroidectomySurgical outcomesThyroid cancerTransoral trans-axillary trans-areolar approaches

Identifiers

PMID40411690
PMCPMC12103400

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.