Evidence map›Paper›PMID 40411643›Full record

ArticleCerebellum (London, England)2025

Cross-Cultural Adaptation of the Patient-Reported Outcome Measure of Ataxia: the Brazilian Version of PROM-Ataxia.

Stephanie Suzanne de Oliveira Scott, Ana Carolina Martins, Gabriel Vasata Furtado, Karina Carvalho Donis, Helena Ashton Prolla, Laura Prolla Lacroix, Ana Laura Brandi, Karine Caregnato Santana, Paulo Ribeiro Nóbrega, Pedro Braga-Neto and 1 more

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Article in Cerebellum (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephanie Suzanne de Oliveira ScottPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil.
Ana Carolina MartinsPrograma de Pós-Graduação em Genética e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Gabriel Vasata FurtadoCentros de Pesquisa Clínica e Experimental, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos 2350, Porto Alegre, 90035-003, Brazil.
Karina Carvalho DonisDepartamento de Genética, Universidade Federal da Paraíba, João Pessoa, Brazil.
Helena Ashton ProllaFaculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Laura Prolla LacroixFaculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Ana Laura BrandiFaculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Karine Caregnato SantanaFaculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Paulo Ribeiro NóbregaDepartamento de Medicina Clínica, Universidade Federal do Ceará, Fortaleza, Brazil.
Pedro Braga-NetoPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil.
Laura Bannach JardimPrograma de Pós-Graduação em Genética e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. ljardim@hcpa.edu.br.ORCID http://orcid.org/0000-0001-6907-5068

Funding

Hospital de Clínicas de Porto Alegre 2023-0565
6 · The paper itself

Abstract

backgroundPatient-Reported Outcome Measure (PROMs) are essential instruments for assessing outcomes in clinical trials, as they represent, in a standardized way, the direct report of patients about their own experiences with the disease. To better understand the health and well-being of the population with ataxia, the Patient-Reported Outcome Measure of Ataxia (PROM-Ataxia) was developed in English.

aimto translate the PROM-Ataxia to Portuguese and culturally adapt it for use in Brazil.

methodsWe followed the ISPOR TCA Task Force guidelines. Researchers from two geographically and culturally distant ataxia care centers, located 4,200 km apart, produced two initial versions in Portuguese. The reconciled version was back translated, improved by the opinion of other specialists in ataxia in the country, and sent to the original author, who approved the preliminary Brazilian version. This version was then taken to cognitive debriefing with ataxic patients followed at one of the two participant sites - Porto Alegre and Fortaleza.

resultsFourteen Brazilian patients participated in the debriefing. They found PROM-ataxia to be adequate and to cover all the significant impacts of ataxia on their lives. Some items were considered ambiguous. Semantic and conceptual issues were identified and resolved with minor translation changes that improved the cross-cultural adaptation of the questionnaire.

conclusionThe Brazilian version of PROM-ataxia is now complete. Further psychometric studies are needed to validate its efficacy as an outcome measure, particularly in clinical trials. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

AtaxiaCross-Cultural ComparisonPatient Reported Outcome MeasuresAdultAgedBrazilFemaleHumansMaleMiddle AgedSurveys and QuestionnairesTranslationsBrazilCultural AdaptationPatient-reported Outcome Measure of ataxiaPROM-ataxiaTranslation

Identifiers

PMID40411643

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.