Evidence map›Paper›PMID 40411641›Full record

ArticleLasers in medical science2025

ICG/MnO

Dan Ma, Huixiang Lu, Hai Zhang, Anru Liao, Qianrong Peng, Min Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dan MaCollege of Pharmacy, Guizhou University, Guiyang, China.
Huixiang LuCollege of Pharmacy, Guizhou University, Guiyang, China.
Hai ZhangCollege of Pharmacy, Guizhou University, Guiyang, China.
Anru LiaoCollege of Pharmacy, Guizhou University, Guiyang, China.
Qianrong PengChina Tobacco Guizhou Industrial Co., Ltd., Guiyang, China.
Min YangCollege of Pharmacy, Guizhou University, Guiyang, China. 2578973180@qq.com.

Funding

China Tobacco Guizhou Industrial Co. Ltd Z164004the National Natural Science Foundation of China 21562014
6 · The paper itself

Abstract

Hypoxia poses a significant challenge to the efficacy of photodynamic therapy (PDT) for cancer treatment. This study aims to design and synthesize PEGylated liposomes encapsulating MnO₂, indocyanine green (ICG), and H-chain ferritin (HFn) to potentially address hypoxia and enhance the therapeutic outcomes of PDT. PEGylated liposomes (ICG/MnO₂-HFn-mPEG-DSPE-Lip) were constructed with a rod-like structure, incorporating MnO₂ as a hypoxia-modulating agent and ICG as a photosensitizer. The drug loading capacity, stability and safety of liposomes were characterized. Singlet oxygen quantum yield (Φ

Indexed as

Indocyanine GreenLung NeoplasmsManganese CompoundsOxidesPhotochemotherapyPhotosensitizing AgentsA549 CellsHumansLiposomesPolyethylene GlycolsIndocyanine GreenLiposomesManganese Compoundsmanganese dioxideOxidesPhotosensitizing AgentsPolyethylene GlycolsH-chain ferritinHypoxiaIndocyanine greenLiposomesPhototherapy

Identifiers

PMID40411641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.