Observational studyEuropean journal of pediatrics2025
Evaluation of testicular function in 1-2-year-old cryptorchid children with alterations of anti-mullerian hormone after various orchidopexy.
Observational study in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This study assessed testicular function in children with cryptorchidism following different orchidopexy procedures by measuring serum anti-Müllerian hormone (AMH). The aim was to identify clinical factors associated with testicular function recovery by comparing pre- and post-operative levels of AMH, luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone (T), and testicular volume at various time points. This prospective observational cohort study included children aged 1 to 1.5 years diagnosed with cryptorchidism via physical examination and ultrasound. The study evaluated testicular function parameters before and after two different orchidopexy techniques, measured at five intervals. Serum AMH was the primary outcome, with FSH, LH, testosterone, and testicular volume as secondary measures. A control group of 57 healthy male infants aged 1 to 2 years was included for comparative analysis. A total of 138 patients were enrolled, with testicular function evaluated preoperatively and at 10 days, 1 month, 3 months, and 6 months post-surgery. Preoperative AMH levels were significantly higher in unilateral compared to bilateral cryptorchidism (P < 0.05). Postoperatively, AMH levels increased by 3 months in children with palpable testicles and by 6 months in those with non-palpable testicles (P < 0.05), with no significant difference between groups at 6 months. Cases with intraperitoneal release procedures also showed significant AMH increases at 3 and 6 months (P < 0.05), and testicular function improved similarly across surgical techniques.
conclusionOrchidopexy can pose a risk of injury, emphasizing the need for careful treatment planning. While surgical technique did not significantly affect outcomes in children aged 1 to 1.5 years, serum AMH is a valuable tool for preoperative evaluation and prognosis in cryptorchidism. WHAT IS KNOWN: •Cryptorchidism impairs testicular function.•Orchidopexy improves function but varies by technique and testicular position. WHAT IS NEW: •AMH is a sensitive postoperative marker for testicular recovery.•Function improvement is consistent across surgical techniques, with intraperitoneal release showing significant AMH gains by 3-6 months.
Indexed as
Identifiers
40411607What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.